A 5-year Retrospective Review of Experience with Clostridium difficile Associated Diarrhea (CDAD)

Armbruster, Steven; Goldkind, Lawrence

doi:10.14309/00000434-201110002-00371

Cited by 2 publications

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“…We determined the location of onset and attribution for each CDI episode using an algorithm based on the most recent guideline definitions from the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA) 9 . These categories included (1) healthcare facility (HCF)-onset, HCF-associated CDI; (2) community-onset, HCF-associated CDI; (3) community-associated CDI; and (4) indeterminate.…”

Section: Methodsmentioning

confidence: 99%

Clostridium difficile Infection Among Veterans Health Administration Patients

Young‐Xu

Kuntz

Gerding

et al. 2015

Infect. Control Hosp. Epidemiol.

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OBJECTIVETo report on the prevalence and incidence of Clostridium difficile infection (CDI) from 2009 to 2013 among Veterans Healthcare Administration patientsDESIGNA retrospective descriptive analysis of data extracted from a large electronic medical record (EMR) databaseSETTINGData were acquired from VHA healthcare records from 2009 to 2013 that included outpatient clinical visits, long-term care, and hospitalized care as well as pharmacy and laboratory information.RESULTSIn 2009, there were 10,207 CDI episodes, and in 2013, there were 12,143 CDI episodes, an increase of 19.0%. The overall CDI rate increased by 8.4% from 193 episodes per 100,000 patient years in 2009 to 209 episodes per 100,000 patient years in 2013. Of the CDI episodes identified in 2009, 58% were identified during a hospitalization, and 42% were identified in an outpatient setting. In 2013, 44% of the CDI episodes were identified in an outpatient setting.CONCLUSIONThis is one of the largest studies that has utilized timely EMR data to describe the current CDI epidemiology at the VHA. Despite an aging population with greater burden of comorbidity than the general US population, our data show that VHA CDI rates stabilized between 2011 and 2013 following increases likely attributable to the introduction of the more sensitive nucleic acid amplification tests (NAATs). The findings in this report will help establish an accurate benchmark against which both current and future VA CDI prevention initiatives can be measured.Infect. Control Hosp. Epidemiol. 2015;36(9):1038–1045

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Section: Methodsmentioning

confidence: 99%

Clostridium difficile Infection Among Veterans Health Administration Patients

Young‐Xu

Kuntz

Gerding

et al. 2015

Infect. Control Hosp. Epidemiol.

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“…The prevalence of CDI for ICU patients prescribed with antibiotics may be higher than other hospitalized patients and has been reported as 25 % in patients with antibiotic-associated diarrhea [222]. CDI-associated mortality rate may be as high as 9 % [223], and for ICU patients, the unadjusted rate may be as high as 23-37 % [222,224,225]; however, other literature suggests early recognition and treatment of ICU-acquired CDI decreases the risk for mortality [226].…”

Section: Diarrheamentioning

confidence: 99%

Adverse Drug Reactions in the ICU

Moore¹,

Burkhart²

2016

Critical Care Toxicology

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A 5-year Retrospective Review of Experience with Clostridium difficile Associated Diarrhea (CDAD)

Cited by 2 publications

References 0 publications

Clostridium difficile Infection Among Veterans Health Administration Patients

Clostridium difficile Infection Among Veterans Health Administration Patients

Adverse Drug Reactions in the ICU

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