A 5-year retrospective analysis of Necrotizing fasciitis: A single center experiences

Kiralj, Aleksandar; Janjić, Zlata; Nikolić, Jelena; Markov, Borislav; Marinković, Mirjana Marković

doi:10.2298/vsp131223081k

Cited by 12 publications

(5 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…After reviewing the recent literature, the results corroborated closely, with the most common initial signs seen remaining the same: swelling (79%), pain (76.9%) and erythema (69.6%) [Tables 1 and 2 ]. [ 6 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 ]…”

Section: Discussion Of R Esultsmentioning

confidence: 99%

Necrotizing fasciitis: How reliable are the cutaneous signs?

Kiat

Natalie

Lateef

2017

J Emerg Trauma Shock

View full text Add to dashboard Cite

Necrotizing fasciitis (NF) is a surgical emergency. It is often aggressive and characterized by the rapidly progressive inflammatory infection of the fascia that causes extensive necrosis of the subcutaneous tissue and fascia, relatively sparing the muscle and skin tissue. As the disease progresses, thrombosis of the affected cutaneous perforators subsequently devascularizes the overlying skin. The course indeed can be a fulminant one. The diagnosis of NF, especially in the early stages, is extremely challenging, and it can be very close in presentation to other skin and subcutaneous tissue infections. The primary site of the pathology is the deep fascia. Necrosis of the tissues and fascia may manifest as erythema without sharp margins, swelling, warmth, shiny, and exquisitely tender areas. Pain out of proportion to physical examination findings may be observed. The subcutaneous tissue may be firm and indurated such that the underlying muscle groups cannot be distinctly palpated. Eventually, as the overlying skin is stripped of its blood supply, skin necrosis ensues and hemorrhagic bullae form. Bacteremia and sepsis invariably develop when the infection is well established. This paper discusses some of issues related to the cutaneous signs found in NF and also provides a review the current, available literature on the subject matter.

show abstract

Section: Discussion Of R Esultsmentioning

confidence: 99%

Necrotizing fasciitis: How reliable are the cutaneous signs?

Kiat

Natalie

Lateef

2017

J Emerg Trauma Shock

View full text Add to dashboard Cite

show abstract

“…Misdiagnosis such as cellulitis, abscess, and pyoderma was often made in this early stage. 28 We have to find some way to a prompt diagnostics, so that we could reach a more correct diagnosis in the future.…”

Section: Could Be the Lack Of A Standard Diagnostics Issue?mentioning

confidence: 99%

Management of Necrotizing Fasciitis and Its Surgical Aspects

Sun

Xie

2015

The International Journal of Lower Extremity Wounds

View full text Add to dashboard Cite

Necrotizing fasciitis (NF) is a severe and rapidly progressive infectious disease that attacks superficial an as well as deep fascia, subcutaneous fat tissue, and muscle. Although the incidence is of relatively low frequency, the median mortality is high. NF is a great burden to patients and hospitals. The most common cause of NF is trauma injuries, followed by other conditions with comorbidity. A classification for NF was presented concerning microbial cause, depth of infection, and anatomy. But the value of classification is not convincing. Early diagnosis of NF is essential and still to be realized by far. Information from clinic or laboratory might contribute to the purpose. Surgery is used in exploration debridement and tissue reconstruction as the main method with NF. Negative pressure wound therapy has proved to be useful in improving wound bed preparation and healing.

show abstract

“…The low incidence of the disease and lack of typical clinical symptoms in its initial phase lead to misdiagnosis as either cellulitis, abscess or pyoderma 7 . “Red flags” for NF are hypotension, hemorrhagic bullae and pain out of proportion 8 .…”

Section: Introductionmentioning

confidence: 99%