A 3D-printed multi-compartment organ-on-chip platform with a tubing-free pump models communication with the lymph node
Sophie R Cook,
Alexander G Ball,
Anwaruddin Mohammad
et al.
Abstract:Multi-organ-on-chip systems (MOOCs) have the potential to mimic communication between organ systems and reveal mechanisms of health and disease. However, many existing MOOCs are challenging for non-experts to implement, due to complex tubing, electronics, or pump mechanisms. In addition, few MOOCs have incorporated immune organs such as the lymph node (LN), limiting their applicability to critical events such as vaccination. Here we developed a 3D-printed, user-friendly device and companion tubing-free impelle… Show more
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