A 30-Year-Single-Center Experience in Atrial Myxomas: From Presentation to Treatment and Prognosis

Obrenović-Kirćanski, Biljana; Mikić, Aleksandar; Parapid, Biljana; Djukić, P.; Kanjuh, Vladimir; Milić, Nataša; Kovačević-Kostić, Nataša; Velinović, Miloš; Seferović, Petar; Vranes, M

doi:10.1055/s-0032-1322545

Cited by 26 publications

(14 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, a prevalence of female sex was found (female/male ratio=2.6: 1). Our results are consistent with previous case studies involving populations from France, Germany, the United States, Austria, and Korea [ 6 , 13 , 14 ].…”

Section: Resultssupporting

confidence: 93%

“…Tumor size in myxomas as a risk factor of embolism was inconsistent in previous studies [ 7 , 13 , 15 , 23 ]. Our study found that tumor size did not differ significantly between the embolic and non-embolic groups.…”

Section: Discussionmentioning

confidence: 95%

“…Tumor size and location are common echocardiographic parameters [ 10 ]. Biljana et al reported that embolization in patients with right atrial myxomas was more frequent [ 13 ]. In our study, we found it very interesting that the atypical myxomas were associated with a higher risk of embolism, a result rarely reported before.…”

Section: Discussionmentioning

confidence: 99%

“…Owing to the retrospective nature and the long period of data collection, some valuable data were overlooked. For instance, the mobility of myxoma depends on its consistency, the level of attachment, and pedicle length, all of which are related to embolic risks [ 7 , 13 , 15 , 23 ]. We found very few cases with pedicle length.…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Risk Factors for Embolism in Cardiac Myxoma: A Retrospective Analysis

Zhang

Liang

et al. 2015

Med Sci Monit

View full text Add to dashboard Cite

BackgroundMyxomas are the most common primary heart tumors and are closely associated with embolic events. Cardiac myxomas typically arise from the interatrial septum at the border of the fossa ovalis in the left atrium. Any other location is considered atypical. Embolism, one of the complications of myxoma, is associated with high morbidity and mortality. The aim of this study was to investigate the risk factors for embolism in patients with cardiac myxoma.Material/MethodsIn this retrospective study, a cohort of 162 patients with cardiac myxomas was surgically treated between January 1998 and June 2014 at 3 cardiac centers in China. Preoperative data, including platelet count, sex, age, and the tumor (size, location, surface, and attachment), were compared between embolic and non-embolic groups of patients.ResultsNo significant differences in vascular risk factors were seen between the 2 groups. However, the percentage of higher platelet count (>300×109/L) and mean platelet volume in the embolic group were significantly higher than in the non-embolic group (P=0.0356, and 0.0113, respectively). Irregular surface and atypical location of the myxomas were also independently associated with increased risk of embolic complications.ConclusionsTumor location, macroscopic appearance, mean platelet volume, and high platelet count are strong risk factors for embolic events in patients with cardiac myxomas.

show abstract

Section: Resultssupporting

confidence: 93%

Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Risk Factors for Embolism in Cardiac Myxoma: A Retrospective Analysis

Zhang

Liang

et al. 2015

Med Sci Monit

View full text Add to dashboard Cite

show abstract

“…Although typically a benign tumour, complications do occur – mainly due to mechanical obstruction caused by the myxoma or embolic phenomena (due to the friable nature of myxomas) (5). Of note, embolization and prolapse of the myxoma through valves are more common in polypoid tumours compared to round/oval myxomas (6).…”

Section: Discussionmentioning

confidence: 99%

Atrialised right ventricular myxoma in a patient with Ebstein’s anomaly

et al. 2018

View full text Add to dashboard Cite

SummaryEbstein’s anomaly is a rare entity affecting around 1 in 200,000 live births and accounts for less than 1% of congenital heart diseases. Ebstein’s anomaly with an associated right-sided myxoma is extremely rare, with only one other case report found in the literature. Previous reports have also noted cases of Ebstein’s anomaly associated with left-sided myxomas. We describe a female patient with, to our knowledge, the first case of a histopathologically confirmed right ventricular myxoma in the setting of Ebstein’s anomaly.Learning points:Tall p waves (Himalayan) are associated with Ebstein’s anomaly.Large a-waves on clinical evaluation are typical of tricuspid valve obstruction or restrictive right ventricular filling.The presence of a stalk is suggestive of a myxoma.Before undertaking surgery, careful evaluation of involved structures including valvular morphology and function is essential.

show abstract

What Influences the Patients with Left Atrial Myxoma: From Embolism to Postoperative Atrial Fibrillation

Xiong

Song

et al. 2020

World j. surg.

View full text Add to dashboard Cite

Background Preoperative embolism and postoperative atrial fibrillation (POAF) are two important factors associated with impaired health conditions and increased economic burden in patients with left atrial (LA) myxoma. The aim of this study was to analyze embolic events, identify predictors of POAF, and evaluate the risk of late-term survival in patients with LA myxoma. Methods From December 2009 to December 2019, 177 consecutive patients with LA myxoma who met the selection criteria were included in the retrospective analysis. Multivariate logistic regression analysis was performed to identify predictors of POAF. Propensity score matching was used for confounder control, and Cox proportional hazards models were used to evaluate the risk of late-term mortality. ResultsThe study population comprised of 125 patients in non-POAF group and 52 patients in POAF group. Preoperative embolism was present in 27.1% of the all cases. By multivariate analysis, age, NYHA functional class III, LA diameter, and cross-clamp time were identified as independent predictors of in-hospital POAF. The overall survival at 1, 5, and 10 years for the 177 patients was 98.9%, 93.7%, and 84.4%, respectively. There was no statistical difference in late-term survival between the two groups in the Cox proportion-adjusted survival curve. After propensity score 1:1 matching, patients with POAF had a longer postoperative hospital stay and Kaplan-Meier survival curve also showed no statistical difference between the two groups. Conclusions Patients with LA myxoma after surgical treatment had a favorable prognosis. In-hospital POAF was not independently associated with late-term mortality in patients with LA myxoma.

show abstract

A 30-Year-Single-Center Experience in Atrial Myxomas: From Presentation to Treatment and Prognosis

Abstract: Symptoms in our cardiac myxoma patients were more pronounced when the myxomas were left-sided, racemous, and over 5 cm in diameter. Even in asymptomatic patients, a high index of suspicion assured timely diagnosis and management.

Cited by 26 publications

References 16 publications

Risk Factors for Embolism in Cardiac Myxoma: A Retrospective Analysis

Risk Factors for Embolism in Cardiac Myxoma: A Retrospective Analysis

Atrialised right ventricular myxoma in a patient with Ebstein’s anomaly

What Influences the Patients with Left Atrial Myxoma: From Embolism to Postoperative Atrial Fibrillation

Contact Info

Product

Resources

About