A 25-year longitudinal, comparison study of the outcome of depression

Brodaty, Henry; Luscombe, Georgina; Peisah, Carmelle; Anstey, Kaarin J.; Andrews, Gavin

doi:10.1017/s0033291701004743

Cited by 71 publications

(66 citation statements)

References 41 publications

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“…Studies of single disorders tend to have a shorter follow-up period, and depend on the severity of the first episode of disorder ; thus, Eaton et al (2008) followed first episodes of depression in a community sample for at least 13 years and showed that half had only a single episode, whereas 35 % had recurrent episodes and 15 % were unremitting. Brodaty et al (2001) followed depressives who had been admitted to hospital for 25 years, and showed that only 12 % had recovered and were well whereas 84 % had had recurrences. Patients attending specialist clinics for anxiety disorders have been followed for shorter periods.…”

Section: Coursementioning

confidence: 99%

Emotional disorders: Cluster 4 of the proposed meta-structure for DSM-V and ICD-11

et al. 2009

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"Emotional disorders: Cluster 4 of the proposed meta-structure for DSM-V and ICD-11." Psychological Medicine.39,12. 2043-2059. http://digitalcommons.wustl.edu/open_access_pubs/3923Emotional disorders: Cluster 4 of the proposed meta-structure for DSM-V and ICD-11Paper 5 of 7 of the thematic section : ' A proposal for a meta-structure for DSM-V and ICD-11 ' Background. The extant major psychiatric classifications DSM-IV, and ICD-10, are atheoretical and largely descriptive. Although this achieves good reliability, the validity of a medical diagnosis would be greatly enhanced by an understanding of risk factors and clinical manifestations. In an effort to group mental disorders on the basis of aetiology, five clusters have been proposed. This paper considers the validity of the fourth cluster, emotional disorders, within that proposal.Method. We reviewed the literature in relation to 11 validating criteria proposed by a Study Group of the DSM-V Task Force, as applied to the cluster of emotional disorders.Results. An emotional cluster of disorders identified using the 11 validators is feasible. Negative affectivity is the defining feature of the emotional cluster. Although there are differences between disorders in the remaining validating criteria, there are similarities that support the feasibility of an emotional cluster. Strong intra-cluster co-morbidity may reflect the action of common risk factors and also shared higher-order symptom dimensions in these emotional disorders.Conclusion. Emotional disorders meet many of the salient criteria proposed by the Study Group of the DSM-V Task Force to suggest a classification cluster.

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Section: Coursementioning

confidence: 99%

Emotional disorders: Cluster 4 of the proposed meta-structure for DSM-V and ICD-11

et al. 2009

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“…Significant numbers of people (up to 80%) who have experienced MDD will experience at least one more episode of MDD later during their lifetime, and 20% will have a chronic course of MDE lasting more than 2 years (Angst, 1986;Keller et al, 1992;Brodaty et al, 2001). …”

Section: Course and Outcome Of Mddmentioning

confidence: 99%

Suicidal Ideation and Attempts Among Psychiatric Patients With Major Depressive Disorder

Sokero¹,

Melartin²,

Rytsälä³

et al. 2003

J. Clin. Psychiatry

311

225

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“…[1][2][3] Guidelines for the treatment of depression, such as those published by the Canadian Network for Mood and Anxiety Treatments (CANMAT) 5 and the National Institute for Health and Clinical Excellence (NICE) in the United Kingdom, 4 often recommend antidepressant treatment in patients with severe symptoms and outline specific risk factors supporting long-term treatment maintenance. 4,5 However, for patients who do not meet the criteria for treatment of depression, the damaging sequelae of depression are frequently compounded without treatment.…”

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confidence: 99%

Predictors of long-term prognosis of depression

Colman

Naicker²,

Zeng³

et al. 2011

Canadian Medical Association Journal

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Research CMAJBackground: Many people with depression experience repeated episodes. Previous research into the predictors of chronic depression has focused primarily on the clinical features of the disease; however, little is known about the broader spectrum of sociodemographic and health factors inherent in its development. Our aim was to identify factors associated with a long-term negative prognosis of depression. Methods:We included 585 people aged 16 years and older who participated in the 2000/01 cycle of the National Population Health Survey and who reported experiencing a major depressive episode in 2000/01. The primary outcome was the course of depression until 2006/07. We grouped individuals into trajectories of depression using growth trajectory models. We included demographic, mental and physical health factors as predictors in the multivariable regression model to compare people with different trajectories.Results: Participants fell into two main depression trajectories: those whose depression resolved and did not recur (44.7%) and those who experienced repeated episodes (55.3%). In the multivariable model, daily smoking (OR 2.68, 95% CI 1.54-4.67), low mastery (i.e., feeling that life circumstances are beyond one's control) (OR 1.10, 95% CI 1.03-1.18) and history of depression (OR 3.5, 95% CI 1.95-6.27) were significant predictors (p < 0.05) of repeated episodes of depression.Interpretation: People with major depression who were current smokers or had low levels of mastery were at an increased risk of repeated episodes of depression. Future studies are needed to confirm the predictive value of these variables and to evaluate their accuracy for diagnosis and as a guide to treatment. Abstract

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A 25-year longitudinal, comparison study of the outcome of depression

Abstract: Even after 25 years, severe depressive disorders appear to have poor long-term outcomes. Patients with chronic outcomes over 15 years can improve when followed over longer periods.

Cited by 71 publications

References 41 publications

Emotional disorders: Cluster 4 of the proposed meta-structure for DSM-V and ICD-11

Emotional disorders: Cluster 4 of the proposed meta-structure for DSM-V and ICD-11

Suicidal Ideation and Attempts Among Psychiatric Patients With Major Depressive Disorder

Predictors of long-term prognosis of depression

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