A 12–month angiographic and optical coherence tomography follow‐up after bioresorbable vascular scaffold implantation in patients with ST‐segment elevation myocardial infarction

Abstract

The OCT revealed a favorable healing pattern after BVS implantation in a STEMI population.

Clinical Outcomes of Bioresorbable Scaffold in Coronary Artery Disease: A Systematic Literature Review

“…We choose to include the DESolve NX study though it was presented but never published as it used the current Novolimus model which is currently CE marked (Tables and ). Of the 31 studies (n = 5,961), 8 studies were performed in STEMI patients, 15 studies were performed in stable CAD patients and 8 studies were classified as “undifferentiated.” Twenty‐five of 31 studies were observational studies with 20 cohort studies and 5 case control studies. There were 6 RCT, including ABSORB III .…”

“…Eight studies (n = 606) including a small phase II RCT TROFI II (n = 95) were reviewed, with study sizes ranging from 11 patients to 290 patients . The duration of follow up ranged from 1 months to 12 months and all utilized the ABSORB BVS.…”

“…TLR rates ranging from 0% to 5.4% (12/546) were reported in 6 of the 8 studies. Of the 12 events, 2 were due to in‐stent restenosis while the remaining were likely due to stent thrombosis . Seven studies reported their rates of stent thrombosis with the rates ranging from 0% to 4.3%.…”

“…Twelve out of 582 patients had stent thrombosis. Three cases of subacute stent thrombosis (on day 9–13) occurred due to the cessation of dual antiplatelet therapy (DAPT) by patients, whilst the others occurred while patients were still on DAPT …”

“…In the acute setting, the use of the ABSORB BVS has shown comparable rates of procedural success, mortality and repeat MI/revascularizations versus DES . However, the rates of stent thrombosis with the use of BVS appear somewhat higher.…”