A 10-Year Tertiary Care Center Experience With Adrenalectomies for Adrenal Tumors

Alghafees, Mohammad A; Musalli, Ziyad F; Albaqami, Khalaf; Alqirnas, Muhannad Q; Alqahtani, Meshari A; Alrasheed, Faisal; Alasker, Ahmed

doi:10.7759/cureus.21949

Cited by 1 publication

(5 citation statements)

References 17 publications

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“…Clinical and histopathological analyses of the resected tumors revealed that pheochromocytoma was the most common hormone-secreting tumor, followed by aldosterone-secreting tumors and steroid-secreting adrenal tumors. Other studies from developing countries yield similar results with an increased prevalence of catecholamine-secreting tumors [ 7 - 9 , 15 ]. Pheochromocytomas typically present with severe headaches and hypertension secondary to the catecholamine surge [ 4 ].…”

Section: Discussionsupporting

confidence: 70%

“…Our study showed that 45.8% of the patients with adrenal mass were aged between 41 and 50 years, while the mean age of all study participants was 47.52 years. A similar study from Saudi Arabia on 55 patients showed similar results where the mean age of patients was 49.91 years [9]. Other studies also report similar findings where more than 35% of the patients were aged between 41 and 50 years [4,14].…”

Section: Discussionsupporting

confidence: 61%

“…This allows the surgeons to accurately locate and characterize the lesion. Moreover, it helps in the accurate delineation and staging of the disease, which are necessary for the decision of optimal surgical treatment [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

“…Surgical resection is considered the gold standard treatment for benign and most early-stage malignant tumors. For several decades, open adrenalectomy was the treatment of choice for adrenal tumors [ 8 , 9 ]. However, minimally invasive laparoscopic adrenalectomy has instantly gained popularity due to fewer complications [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

“…Henceforth, laparoscopic adrenalectomy is considered the better approach for adrenal tumors. Unfortunately, the cost of the procedure, limited resources, expensive equipment, and the lack of trained surgical faculty have made the use of laparoscopic adrenalectomy limited in developing countries [ 8 , 9 ]. As a result, open adrenalectomy is more commonly practiced in public sector hospitals in developing countries such as Pakistan.…”

Section: Introductionmentioning

confidence: 99%

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The Spectrum of Postoperative Complications and Outcomes After Open Adrenalectomy: An Experience From a Developing Country

Zubair¹,

Arif²,

Razzaq³

et al. 2022

Cureus

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BackgroundOpen adrenalectomy is an invasive surgical procedure that is commonly performed for adrenal gland neoplasms in developing countries. Due to its complexity, the patients are predisposed to a number of complications and dismal outcomes. The objective of our study is to assess different characteristics of patients undergoing open adrenalectomy, including their histology, postoperative complications, and outcomes. MethodsThis retrospective cross-sectional study included 107 patients undergoing open adrenalectomy for primary adrenal gland neoplasms. Patients with bilateral involvement, metastatic disease, or unresectable tumors were excluded. Patients were evaluated for different features that included demographic data, tumor properties, postoperative outcomes, and complications. ResultsOut of 107 patients, 45 (42.1%) were females. The mean age of the patients was 47.53 ± 8.45 years. Abdominal pain and severe headaches were the most common presenting complaints. A total of 96 (89.7%) tumors were benign, while 11 (10.3%) were malignant. Upon the histopathological examination of the resected specimen, adrenal adenoma was present in 49 (45.8%) cases, while adrenal pheochromocytoma was present in 41 (38.3%) cases. A total of 51 patients developed different postoperative complications including surgical site infections (22.4%), atelectasis (11.2%), deep venous thrombosis (7.5%), and retroperitoneal hematoma (5.6%). In-hospital mortality occurred in three (2.8%) patients. ConclusionSurgical site infections, atelectasis, deep venous thrombosis, and retroperitoneal hematoma were frequent postoperative complications after open adrenalectomy. These complications increase morbidity and mortality, especially in developing countries. Improved surgical techniques, intraoperative hemostasis, and multidisciplinary approach can yield favorable postoperative outcomes.

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