A 10-year retrospective study of hemangioblastomas of the central nervous system with reference to von Hippel–Lindau (VHL) disease

Imaging Diagnosis—magnetic Resonance Imaging Features of a Cerebral Hemangioblastoma in a Dog

“…1, 5 They can be single or multiple, sporadic, or familial, with the latter seen in association with Von Hippel-Lindau syndrome. 6 This is a familial multisystem disorder characterized by retinal hemangioblastoma and a number of extraneural neoplasms or cysts, including renal cell carcinoma, pheochromocytoma, and cysts of the kidneys, liver, or pancreas. 7 The nature of the interstitial cell population and its neoplastic capacity compared to that of the conventional vascular component in hemangioblastoma have been a subject of debate in the human literature.…”

Differentiation of hemangioblastomas from pilocytic astrocytomas using 3-T magnetic resonance perfusion-weighted imaging and MR spectroscopy

“…However, hemangioblastomas are more vascular than PAs, which has important surgical and clinical implication. The surgical resection of hemangioblastomas could lead to high mortality and morbidity rates, which is often related to the complication of excessive bleeding [4,5]. Thus, a reliable preoperative differentiation between them is important.…”

Intradural–extramedullary haemangioblastoma with paraspinal extension in a dog

“…Spinal cord localisation of a haemangioblastoma is unusual; most clinical reports of the disease in humans describe intramedullary tumours, whereas intradural extramedullary growth is extremely rare . These tumours represent approximately 2–10% of all spinal cord neoplasms in people and can occur sporadically or as a part of the Von Hippel‐Lindau syndrome …”