Abstract:Aim: The aim of this study is to formulate and evaluate of baclofen transdermal patches using different polymers, penetration enhancers, and plasticizers. A drug with different film forming polymers was subjected to compatibility study. In addition, in-vitro permeation across animal skin for the best formulation was investigated. Materials and Methods: After studying the incompatibility of baclofen and other polymers used, the pure drug baclofen was formulated as transdermal patches composed of different polym… Show more
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