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Abstract

The contemporary development in the drug delivery system is a seamless process. Any delivery system targeting a molecule to a particular site is always been appreciated. This requirement can be fulfilled through a specialized drug delivery system that can easily target the drug at the site of action without compromising its efficacy and quality. Few new drugs typically cannot be effectually delivered by conventional dosage form. Hence, benefits from targeted, localized delivery of therapeutic agents are other driving forces for the current scenario. Nanosponge technology has been introduced to assist the release of drug in a controlled manner over time to reduce systemic toxicity and severe reactions. Nanosponges are tiny sponges with a size of about a virus (250 nm-1 μm), which consist of cavities that can be filled with a wide variety of hydrophilic as well as hydrophobic drugs, which can be further incorporated into a pharmaceutical dosage form such as oral, parenteral, topical or inhalation. The sighting of nanosponge has become a noteworthy step in overcoming certain problems such as drug toxicity, poor bioavailability, physiochemical instability , and patient non-acceptability. INTRODUCTION: Authentic targeted drug delivery systems have been a fantasy for always in the past and today as well. But it has been mainly unsatisfied by the difficult chemistry that is involved in the new development systems. Targeting drug delivery has long been problematic for medical investigators, i.e., how to get them to the right place in the body and how to control the release of the drug to prevent overdoses.