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Dangoor, Joseph Yoav; Hakim, David; Singh, Rajinder; Hakim, Nadey

doi:10.6002/ect.2014.0258

Cited by 4 publications

(1 citation statement)

References 24 publications

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“…The advancement in transplantation has given the world a new source of treatment for end-stage kidney failure (1). Nevertheless, the shortage of donated organ has severely impeded the number of transplantation in many countries, and Malaysia is no exception (2).…”

Section: Introductionmentioning

confidence: 99%

Attendance and Institutional Facilities of Long-Term Kidney Donors Follow-Up

Makmor¹,

Ms²,

Noriza³

et al. 2016

JUMMEC

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Section: Introductionmentioning

confidence: 99%

Attendance and Institutional Facilities of Long-Term Kidney Donors Follow-Up

Makmor¹,

Ms²,

Noriza³

et al. 2016

JUMMEC

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How Surgical Research Gave Birth to a New Clinical Surgical Field: A Viewpoint from the Dallas Uterus Transplant Study

et al. 2023

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Background: Uterus transplantation (UTx) has come of age in the 21st Century, building on the 20th Century developments in vascular anastomosis and effective immunosuppressive protocols enabling solid organ transplantation to become the life extending and life improving treatment option we know today. However, UTx has the goal of enabling reproduction, meaning that research focused on establishment of pregnancy and healthy live birth in addition to surgical technique and immunosuppression. Summary: The Dallas UtErus Transplant Study (DUETS), established at Baylor University Medical Center in 2015 is one of four UTx programs in the United States, and holds the distinction of being home not only to the first U.S. live birth, but also the highest volume UTx program worldwide, with 23 uterus transplants performed to date, resulting in 15 live births. Innovations pioneered at our center span all aspects of the Utx process, seeking to improve success in terms of achieving pregnancy and live birth, while also minimizing the burden on donors and recipients. The have included: 1) a deceased donor hysterectomy approach that allows the uterus to be procured prior to cross-clamp; 2) proof of concept with use of only superior uterine veins after procuring both the superior and inferior uterine veins during the donor surgery, enabling the choice of the best option in terms of size and location for outflow, while also preserving ovary viability in living donors; 3) contribution to robot assisted technique/minimal invasive technique with vaginal extraction of the uterus graft for living donor surgeries, shortening donor recovery times; 4) developing a robot-assisted technique for graft hysterectomies, improving recovery times for recipients at the end of their UTx journey; 5) refining immunosuppression protocols to enable embryo transfer 3 months after induction therapy, increasing recipients’ chances for achieving up to two live births during the 5 years post-transplant the UTx protocol specifies; and 6) building on our clinical trial experience to now offer UTx in the U.S. outside of a clinical study. Key Messages: Our center along with others throughout the world have demonstrated that UTx can be reproducible, result in live births from both living and deceased donors, and safely introduced as a clinical option. Due to the complexity of UTx as well as the need for long-term multidisciplinary care, centers implementing UTx should have an established abdominal transplant program, gynecologic surgery program, high-risk obstetric and neonatal care, and institutional support and oversight, and should partner with established UTx programs for protocol development and operative proctoring.

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Pre-hepatic and pre-pancreatic transplant donor evaluation

Cahalane¹,

Mojtahed²,

Sahani³

et al. 2019

Cardiovasc. Diagn. Ther.

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Innovations in surgical techniques coupled with advances in medical and pharmacological management in the past few decades have enabled organ transplantation to become integral to the management of end stage organ failure. In this review article, we will review the role of the radiologist in the work up of liver and pancreas donors during evaluation of their donor candidacy. The critical role of imaging in assessing the parenchymal, biliary and vascular anatomy in liver donor candidates will be reviewed, as well as highlighting the anatomical findings that may pose a contraindication to transplantation. The limited role of imaging in pancreas donor evaluation is also covered, as well as a brief overview of the surgical techniques available and how the radiologist's findings influence operative technique selection.

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Untitled

Cited by 4 publications

References 24 publications

Attendance and Institutional Facilities of Long-Term Kidney Donors Follow-Up

Attendance and Institutional Facilities of Long-Term Kidney Donors Follow-Up

How Surgical Research Gave Birth to a New Clinical Surgical Field: A Viewpoint from the Dallas Uterus Transplant Study

Pre-hepatic and pre-pancreatic transplant donor evaluation

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