Abstract:Pancreatitis is a common adverse reaction to asparaginase and a reason for drug discontinuation in patients with acute lymphoblastic leukemia. Diagnostic criteria include elevated pancreatic enzymes, abdominal symptoms and/ or imaging findings suggestive of pancreatitis. There is no specific treatment, but in a few reports, octreotide seems to be an effective drug in reducing acute complications and mortality. Here we describe the case of a child who developed asparaginase-induced necrotizing pancreatitis, suc… Show more
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