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Cl, Martel; Jb, Mackic; Jd, Adams; Jg, McComb; Mh, Weiss; Bv, Zlokovic

doi:10.1023/a:1016007601794

Cited by 14 publications

(2 citation statements)

References 12 publications

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“…It has been reported that the increased level of dopamine in blood (hyperdopaminemia) could be caused by long‐lasting, obsessive eating of bananas by the patients who suffer from anorexia nervosa [] resulted in psychological changes. Though, it is generally believed that circulating dopamine do not penetrate blood–brain barrier, in long‐term arterial infusion studies, a saturable dopamine influx into brain was demonstrated []. Determination of dopamine in banana could be interesting from both dietary and biomedical point of views.…”

Section: Introductionmentioning

confidence: 99%

“…2‐(3,4‐Dihydroxyphenyl)ethylamine (dopamine) is an important neurotransmitter involved in motor and cognitive functions [], and plays a significant role in cardiovascular, renal, and hormonal systems even at very low concentration []. In the present work, dopamine was selected as the target analyte, 2‐(3,4‐dimethoxyphenyl)ethylamine imprinted polymer (MIP pt ) as the sorbent, and banana fruits as a real sample.…”

Section: Introductionmentioning

confidence: 99%

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Effective separation of dopamine from bananas on 2‐(3,4‐dimethoxyphenyl)ethylamine imprinted polymer

Luliński¹,

Maciejewska

2012

J of Separation Science

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A 2-(3,4-dimethoxyphenyl)ethylamine imprinted polymer (MIP(pt) ) was prepared via the precipitation polymerization together with a nonimprinted polymer (NIP). The morphology of particles was investigated by scanning electron microscopy and the specific surface areas were estimated by methylene blue adsorption (60.5 ± 3.5 and 36.9 ± 1.2 m(2)/g for MIP(pt) and NIP, respectively). The binding experiments were performed to determine the binding capacity of MIP(pt)/NIP particles toward dopamine. Next, the effects of solvents on loading, washing, and eluting steps were examined on solid-phase extraction (SPE). Methanol-water 85:15 v/v (loading step), methanol (washing step), and 0.04 M aqueous ammonium acetate-methanol 30:70 v/v (eluting step) were selected as the most effective systems. Described SPE protocol was successfully applied for separation of dopamine on 2-(3,4-dimethoxyphenyl)ethylamine imprinted particles. Finally, the molecularly imprinted polymer was used for determination of dopamine in spiked banana extract. The total recovery of dopamine from MIP(pt) was equal to 88.5 ± 4.6%, but from NIP was only 12.8 ± 2.3%. The developed material and method were demonstrated to be applicable for the separation of dopamine from bananas. The commercial sorbent C18 was not suitable to such application.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%