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Abstract

Pituitary Stalk Interruption Syndrome (PSIS) is characterized by association of an absent or thin pituitary stalk, an absent or hypoplastic anterior pituitary lobe and/or an ectopic posterior pituitary lobe [1]. This syndrome belongs to the spectrum of midline abnormalities and is often associated with other midline extra-pituitary malformations [2]. The importance of its diagnosis lies on the basis that it leads to complete and permanent form of anterior pituitary hormone deficiency which occurs in varied fashion. We present to you a case duplet of PSIS with two different forms of presentation and pituitary morphology.