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Abstract

Surface functionalized gold nanoparticles that mimic the coupling between merozoites and erythrocytes are proposed for antimalarial medicines and the strategic design is theoretically described. As for the interaction between the gold nanoparticles and the merozoites, the former acts as the adhesive balls for merozoites. This will lead to blocking the invasion of merozoites into red blood cells by suppressing the movement of merozoites on the surfaces of red blood cells.