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Bulgakova, N. A.; Gornostaev, L. M.

doi:10.1023/a:1013164528653

Cited by 6 publications

(5 citation statements)

References 1 publication

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“…Щоб уникнути гідроксипохідного, ми використали два основні шляхи синтезу триазенів. Перший методвикористання діазотованого аміноантрахінону та вільного аміну [14]. Другий метод використання вільного аміноантрахінону та діазотованого ароматичного аміну.…”

Section: результати досліджень та їх обговоренняunclassified

Features of Synthesis of Triazenes of the Anthraquinone Series

Taras¹,

Dejchakivsky²,

Shupeniuk³

et al. 2019

CTAS

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Прикарпатський національний університет імені Василя Стефаника, кафедра хімії середовища та хімічної освіти 2 Національний університет "Львівська політехніка", кафедра технології біологічно активних сполук, фармації та біотехнології,

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Section: результати досліджень та їх обговоренняunclassified

Features of Synthesis of Triazenes of the Anthraquinone Series

Taras¹,

Dejchakivsky²,

Shupeniuk³

et al. 2019

CTAS

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“…In particular, 9,10-anthracenedione derivatives have been condensed with anthrimidecarbazole, imidazole, oxazole, thiazole, phthaloylacridine, and pyrazine rings [9]. In addition, the literature contains information related to annulation of the 9,10-anthracenedione structure using triazole [10], pyrazole, and pyridazine nuclei [11][12][13].…”

Section: Introductionmentioning

confidence: 99%

“…= 293-294 • C 1. H-NMR (CF 3 COOD): δ = 10.12-10.08 (m, 1H, CH ar ),10.01 (d, 1H, J = 8.3 Hz, CH ar ), 9.62 (d, 1H, J = 8.3 Hz, CH ar ), 9.53 (d, 1H, J = 6.3 Hz, CH ar ), 9.41 (d, 1H, J = 6.4 Hz, CH ar ), 9.35-9.30 (m, 1H, CH ar ), 9.04-8.99 (m, 2H, CH ar ), 3.93 (s, 3H, CH 3 ), 3.63 (s, 3H, CH 3 ). 13 C-NMR (CF 3 COOD): δ = 188.22, 184.11, 155.54 (C=O), 150.00, 145.47, 140.94, 138.84, 137.20 (2C), 137.12, 133.70, 133.00, 132.35, 128.91, 128.89, 127.67, 126.65, 125.56, 119.02, 117.76 (C ar ), 17.33, 15.47 (CH 3 ).…”

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confidence: 99%

A Ring Opening–Annulation Reaction of Anthra[1,2-d][1,2,3]triazine-4,7,12(3H)-trione in the Presence of Pyridines as an Efficient Approach to the Construction of Naphtho[2,3-H]pyrido(quinolino)[2,1-b]quinazoline System

Zvarych

Stasevych²,

Русанов³

et al. 2022

Molecules

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The [1,2,3]triazin-4(3H)-one ring is a synthetically important molecular platform for a variety of chemical transformations. Despite this, currently, there has been little research on the reaction of the thermal opening of the [1,2,3]triazin-4(3H)-one nucleus. In this work, we describe the synthetic potential of anthra[1,2-d][1,2,3]triazine-4,7,12(3H)-trione in the reaction of the thermal opening of a cycle following the [4+2]-cycloaddition reaction with a number of pyridine derivatives and quinoline. It is shown that this method is effective for the synthesis of the 6H-naphtho[2,3-H]pyrido(quinolino)[2,1-b]quinazoline-6,9,14-trione system. We also investigate the influence of the position of substituents in the structure of pyridine on the formation characteristics of the target products.

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“…There are almost no published data on chemical properties of triazenyl-substituted anthraquinones [ 10 , 11 ]. Triazene moiety is a known alkylating carcinolytic group.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and In Silico Study of 4-Substituted 1-Aminoanthraquinones

Shupeniuk

Nepolraj²,

Taras

et al. 2021

Russ J Org Chem

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Eight new 4-substituted 1-amino-9,10-anthraquinones containing a primary amino group were synthe sized by nucleophilic substitution of bromine in 1-amino-4-bromo-9,10-anthraquinones. 1-Amino-4-[2-(hydroxy ethyl)amino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid containing a biogenic amine fragment (2-aminoethanol) was converted into the corresponding 1-triazenyl derivatives. The structure of the synthesized compounds was determined on the basis of the LC/MS and 13 C and 1 H NMR data, and their drug likeness was estimated in silico. Compounds with a good drug likeness score were analyzed by DIGEP-Pred, their possible interactions with proteins were simulated using STRING, and their biological activity was interpreted using the Kyoto Encyclopedia of Genes and Genomes.

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Cited by 6 publications

References 1 publication

Features of Synthesis of Triazenes of the Anthraquinone Series

Features of Synthesis of Triazenes of the Anthraquinone Series

A Ring Opening–Annulation Reaction of Anthra[1,2-d][1,2,3]triazine-4,7,12(3H)-trione in the Presence of Pyridines as an Efficient Approach to the Construction of Naphtho[2,3-H]pyrido(quinolino)[2,1-b]quinazoline System

Synthesis and In Silico Study of 4-Substituted 1-Aminoanthraquinones

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