Untitled

Shinitzky, Meir; Nudelman, Fabio; Barda, Yaniv; Haimovitz, Rachel; Chen, Effie; Deamer, David W.

doi:10.1023/a:1020535415283

Cited by 56 publications

(45 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…By an accurate comparison of the spectral behavior of the two enantiomers, the occurrence of significant differences in these interactions has been excluded, leaving without a direct experimental evidence able to explain their different solubility in AOT micellar solution. Unless one wants to speculate about minute energy differences between the two enantiomers [22], one needs to consider the possibility of different amounts of water or chiral contaminant traces in the micellar solutions and/or recognition of a single AOT configuration.…”

Section: Discussionmentioning

confidence: 99%

Confinement of chiral molecules in reverse micelles: FT-IR, polarimetric and VCD investigation on the state of dimethyl tartrate in sodium bis(2-ethylhexyl) sulfosuccinate reverse micelles dispersed in carbon tetrachloride

Abbate

Longhi

Ruggirello

et al. 2008

Colloids and Surfaces A: Physicochemical and Engineering Aspect

View full text Add to dashboard Cite

a b s t r a c tThe state of d and l-dimethyl tartrate confined within dry sodium bis(2-ethylhexyl) sulfosuccinate (AOT) reverse micelles dispersed in CCl 4 has been investigated by FT-IR spectroscopy, polarimetry, and vibrational circular dichroism (VCD). Measurements have been performed at 25 • C as a function of the solubilizate-to-surfactant molar ratio (R) at a fixed AOT concentration (0.158 M). The analysis of experimental data is consistent with the hypothesis that both enantiomers of dimethyl tartrate are mainly entrapped in the reverse micelles and located in proximity to the surfactant head-group region. The formation of this interesting self-organized chiral nanostructure involves some changes of the typical H-bonding of dimethyl tartrates in the pure solid state or as monomers dispersed in CCl 4 attributable to the establishment of specific solubilizate/surfactant head-group interactions and confinement effects.

show abstract

Section: Discussionmentioning

confidence: 99%

Confinement of chiral molecules in reverse micelles: FT-IR, polarimetric and VCD investigation on the state of dimethyl tartrate in sodium bis(2-ethylhexyl) sulfosuccinate reverse micelles dispersed in carbon tetrachloride

Abbate

Longhi

Ruggirello

et al. 2008

Colloids and Surfaces A: Physicochemical and Engineering Aspect

View full text Add to dashboard Cite

show abstract

“…A number of experimental techniques have been proposed for the observation of PV in molecular systems, including rovibrational 11 , electronic [12][13][14] , Mössbauer 15 and NMR 16 spectroscopy, as well as crystallization 17 and solubility 18 experiments, or optical activity measurements 19 , but no unambiguous observation has so far been made. After the pioneering work of Yamagata 1 , Rein 2 , and Gajzago and Marx 3 who first suggested that weak interaction is responsible for an energy difference in the spectrum of right-and left-handed chiral molecules, Letokhov proposed in 1975 to observe PV effects in molecules as a difference 11 After a first test on separated enantiomers of camphor in 1977 20 , the most sensitive experiments to date following Lethokov's proposal were performed around 2000 by authors of this paper.…”

Section: Introduction: Context and Historymentioning

confidence: 99%

High resolution spectroscopy of methyltrioxorhenium: towards the observation of parity violation in chiral molecules

Stoeffler

Darquié

Shelkovnikov

et al. 2011

Phys. Chem. Chem. Phys.

View full text Add to dashboard Cite

Originating from the weak interaction, parity violation in chiral molecules has been considered as a possible origin of the biohomochirality. It was predicted in 1974 but has never been observed so far. Parity violation should lead to a very tiny frequency difference in the rovibrational spectra of the enantiomers of a chiral molecule. We have proposed to observe this predicted frequency difference using the two photon Ramsey fringes technique on a supersonic beam. Promising candidates for this experiment are chiral oxorhenium complexes, which present a large effect, can be synthesized in large quantity and enantiopure form, and can be seeded in a molecular beam. As a first step towards our objective, a detailed spectroscopic study of methyltrioxorhenium (MTO) has been undertaken. It is an ideal test molecule as the achiral parent molecule of chiral candidates for the parity violation experiment. For the 187 Re MTO isotopologue, a combined analysis of Fourier transform microwave and infrared spectra as well as ultra-high resolution CO 2 laser absorption spectra enabled the assignment of 28 rotational lines and 71 rovibrational lines, some of them with a resolved hyperfine structure. A set of spectroscopic parameters in the ground and first excited state, including hyperfine structure constants, was obtained for the ν as antisymmetric Re=O stretching mode of this molecule. This result validates the experimental approach to be followed once a chiral derivative of MTO will be synthesized, and shows the benefit of the combination of several spectroscopic techniques in different spectral regions, with different set-ups and resolutions. First high resolution spectra of jet-cooled MTO, obtained on the setup being developed for the observation of molecular parity violation, are shown, which constitutes a major step towards the targeted objective. † Supplementary information available in the ancillary file: Measured and fitted transition frequencies as well as spectroscopic constants.1

show abstract

“…Ramachandran and Natarajan [70] showed that L-tyrosine crystallizes in silica gel having spherulitic morphology with long needles. This is also true regarding the crystallization experiment of Shinitzky et al [27] (D. Deamer, personal communication). Dendritic pattern of liquid-crystal growth in organic materials is a common place [71].…”

Section: Justificationmentioning

confidence: 71%

“…Their data also show that crystalliza-tion of racemic D, L-Asn yielded preferential formation of L-crystals over D-crystals, the fact that was left unexplained. In essence, this is another manifestation of "unexpected difference between D-and L-" enantiomers discussed by Shinitsky et al [27].…”

Section: Introductionmentioning

confidence: 81%

“…Shinitsky et al [27] observed "unexpected difference in the solubilities of D-and L-tyrosine in water, which could be discerned by their rate of crystallization and the resulting concentrations of their saturated solutions". This effect is neither due to the difference in D-and Lequilibrium crystal structures, enantiomeric impurity, surface of the vessel, nor due to secondary nucleation.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

On the Origin of Biological Functions

Umantsev¹

2011

JMP

View full text Add to dashboard Cite

We consider the problem of structure and functions of the first forms of living matter and present a hypothesis that they were formed through a physico-chemical process known as dendritic crystallization. According to this hypothesis the branching, dendritic structures helped build living systems by lending them functions so that organic chemical evolution is just one natural consequence of the evolution of matter in the universe. We conclude that a self-replicating biological system with adaptation emerged from simple molecules using completely abiotic mechanism of formation, which acted simultaneously or intermittently at different places on the early Earth and created similar structures everywhere. The dendritic hypothesis of origin of the functions explains similarities in the living systems and supports the assumption of a 'second genesis of life'. The dendritic scenario does not need carbon/phosphorus-based solutes in water-based solutions, which may have important implications for exobiology and extraterrestrial origin-of-life scenarios. An experiment to test the hypothesis is suggested.

show abstract

Untitled

Cited by 56 publications

References 14 publications

Confinement of chiral molecules in reverse micelles: FT-IR, polarimetric and VCD investigation on the state of dimethyl tartrate in sodium bis(2-ethylhexyl) sulfosuccinate reverse micelles dispersed in carbon tetrachloride

Confinement of chiral molecules in reverse micelles: FT-IR, polarimetric and VCD investigation on the state of dimethyl tartrate in sodium bis(2-ethylhexyl) sulfosuccinate reverse micelles dispersed in carbon tetrachloride

High resolution spectroscopy of methyltrioxorhenium: towards the observation of parity violation in chiral molecules

On the Origin of Biological Functions

Contact Info

Product

Resources

About