2022
DOI: 10.13040/ijpsr.0975-8232.13(12).4805-18
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Abstract: Severe viral infections like Covid-19 are emerging now a day and are the common causes of human illness and death. Presently, we have a limited availability of antiviral chemotherapeutic agents to prevent and treat these infections, so it is the need of an hour to develop potential antiviral drugs against various harmful and fatal viral infections. A large quantity of research has been performed on 1,2,3 triazole and their derivatives, which has proved the promising antiviral activity of this heterocyclic nucl… Show more

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“…Nitrogen heterocycles have been extensively studied for their overall medicinal properties ( Heravi and Zadsirjan, 2020 ; Kerru et al, 2020 ) and in particular—antimicrobial activity, both antibacterial and antifungal. 1,2,3-Triazoles, in particular, have gained attention due to their structural versatility and potential for diverse biological activities—antimicrobial ( Banu et al, 1999 ; Yadav et al, 2023 ), antiviral ( Viegas et al, 2020 ; Chopade and Shaikh, 2022 ), anticancer ( Slavova et al, 2020 ; Alam, 2022 ), anti-inflammatory ( Kuntala et al, 2021 ; Matin et al, 2022 ), central nervous system ( Silalai et al, 2022 ; Khan et al, 2023 ), anti-SARS-CoV-2 ( Hamadi et al, 2022 ) to name a few. A vast amount of experimentation and literature reports on novel antimicrobial 1,2,3-triazoles has been accumulated over the years and the pace of research efforts seems to only accelerate.…”
Section: Introductionmentioning
confidence: 99%
“…Nitrogen heterocycles have been extensively studied for their overall medicinal properties ( Heravi and Zadsirjan, 2020 ; Kerru et al, 2020 ) and in particular—antimicrobial activity, both antibacterial and antifungal. 1,2,3-Triazoles, in particular, have gained attention due to their structural versatility and potential for diverse biological activities—antimicrobial ( Banu et al, 1999 ; Yadav et al, 2023 ), antiviral ( Viegas et al, 2020 ; Chopade and Shaikh, 2022 ), anticancer ( Slavova et al, 2020 ; Alam, 2022 ), anti-inflammatory ( Kuntala et al, 2021 ; Matin et al, 2022 ), central nervous system ( Silalai et al, 2022 ; Khan et al, 2023 ), anti-SARS-CoV-2 ( Hamadi et al, 2022 ) to name a few. A vast amount of experimentation and literature reports on novel antimicrobial 1,2,3-triazoles has been accumulated over the years and the pace of research efforts seems to only accelerate.…”
Section: Introductionmentioning
confidence: 99%