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Abstract

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), detected first in China, spread out fast to other parts of the world, and was soon recognized as a pandemic in March 2020. According to WHO, 179.686.071 confirmed cases and 3.899.172 deaths due to new coronavirus were reported worldwide on 26th June 2021. Despite countless efforts in searching for repositioned drugs to treat this disease, the results are still modest. Thus, the search for new molecular entities in the treatment of COVID-19 is an essential field in medicinal chemistry. Since the pandemic's beginning, several studies have reported the synthesis of novel organic compounds and their in silico interactions with the new coronavirus. Such computational studies are currently being applied to unveil the complexities of drug-target molecule interaction and also helping in developing new pharmacological treatments. This systematic review aims to provide an overview of studies describing the utilization of novel compounds as prospective drugs in the treatment of COVID-19.

Contaminant removal processes from soil

“…It could be classified as physical, biological, chemical, or radiological substances that, in high enough quantities and harm living organisms through air, soil, food, and water. A pollutant causes damage to people or animals (Verma et al, 2022). For example, in the environment chlorine gas does not naturally exist, so it is a pollutant; but, once it is introduced into the air as a result of human-induced action, it will be a pollutant due to its adverse impacts on homo sapiens as well as wildlife.…”