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Kim, Hye Rim; Choi, Jung Hwa; Park, Won Gyu

doi:10.4194/1303-2712-v13_2_07

Cited by 3 publications

(1 citation statement)

References 26 publications

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“…Photoinduced toxicity of antibiotics such as fluoroquinolones, sulfonamides, and tetracyclines has been clinically recognized, [49–51] with fluoroquinolones being particularly involved in the production of reactive oxygen species such as 1 O 2 and O 2 ⋅ −[17,52] when exposed to UV irradiation. LOM, a fluoroquinolone antibiotic drug, is one of the most phototoxic drugs upon UV exposure by the MS method, [53] thus, the photodegradation behaviour of differently charged LOM species (e. g., HLOM + , LOM 0 , and H + LOM − ) was investigated by monitoring the DPV response at an interval of 1 min till 20 min when excited with a light source of λ=365 nm.…”

Section: Resultsmentioning

confidence: 99%

Voltammetric Study of Lomefloxacin Transfer at the Interface between Two Immiscible Electrolyte Solutions: Ionic Partition, Photodegradation, and Sensing Applications

et al. 2022

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The transfer of ionizable lomefloxacin (LOM) across a polarized interface between two immiscible electrolyte solutions (ITIES) was studied using cyclic and differential pulse voltammetry (DPV). The pH values of water (ionic strength=0.02 M) interfacing with the 1,2‐dichloroethane phase were varied to investigate the transfer behavior of differently charged LOM species, including protonated, neutral, and zwitterionic forms of LOM, namely HLOM+, LOM0, and H+LOM−. An ionic partition diagram for LOM was drawn with DPV response at various pH values, and the distinctive features of LOM were compared to those of fluoroquinolone antibiotics, which have similar pKa values. Physical and thermodynamic properties, including the formal transfer potential, lipophilicity, and Gibbs free energy of transfer of LOM were also evaluated. Furthermore, the photodegradation properties of differently charged LOM species and ophthalmic LOM drop samples (pH 5.0) were investigated after exposure to a UV (λ=365 nm) source. Quantitative analysis of HLOM+ concentrations in buffer and diluted commercial eye drop solutions containing LOM was finally demonstrated using differential pulse stripping voltammetric responses at pH 3.0 and 5.0 involving the transfer of HLOM+ at a polarized microhole‐water/polyvinylchloride‐2‐nitropheyloctylether gel interface.

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Section: Resultsmentioning

confidence: 99%

Voltammetric Study of Lomefloxacin Transfer at the Interface between Two Immiscible Electrolyte Solutions: Ionic Partition, Photodegradation, and Sensing Applications

et al. 2022

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Genetic Diversity and Population Genetic Structure of Korean Black Scraper Thamnaconus modestus in Korea and Japan Based on the mtDNA Marker

Gwak

Roy

2021

Ocean Sci. J.

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Changes in growth, morphology, and levels of digestive enzymes and growth-related hormones in early ontogeny of black scraper, Thamnaconus modestus

Liu,

Zeng,

Zhang

et al. 2024

Front. Mar. Sci.

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IntroductionThe black scraper, Thamnaconus modestus, is a highly valued marine fish species, but its output has gradually decreased in recent years, which may be due to its low survival rate during early ontogenesis.MethodsTherefore, in this study, we assessed the changes in growth, morphology, digestive enzymes, and hormone levels in T. modestus from 0–60 days post-hatching (dph) and revealed growth turning points by morphological measurement and determination of digestive enzyme activities and hormone levels. We found that ontogenesis could be divided into the larval (0–20 dph) and juvenile (20–60 dph) stages. Acid and alkaline protease activity significantly increased and decreased, respectively, from 12–25 dph, likely due to the development of stomach and gastric glands. Acid phosphatase levels significantly increased at 0 and 4 dph, which may be related to the regulation of metabolism and immune protection. A sharp increase in alkaline phosphatase levels at 20 and 25 dph was observed and was likely due to the development of the brush border membrane of enterocytes. The amylase level was significantly higher at 25, 30, and 35 dph, possibly due to better digestion and absorption during the transition from consuming Artemia to compound feed. In newly hatched larvae, the level of thyroid hormones triiodothyronine (T3) and thyroxine (T4) gradually increased and peaked at 35 dph, highlighting the importance of these hormones during the development of T. modestus. Growth hormone (GH) levels first increased from 0–8 dph, with a plateau at 8–20 dph, and then increased at 25–30–35 dph. For insulin-like growth factor 1 (IGF-1), a significant increase with a subsequent plateau was observed between 8 and 20 dph, followed by a substantial decrease between 30 and 35 dph. These results suggest that the regulating functions of GH and IGF-1 are synchronised. Digestive enzyme activity and hormone levels of abnormal fry at 30 dph were lower than those of normal fish, highlighting the importance of specific hormones, especially T4 and IGF-1, in the development of T. modestus.

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Untitled

Cited by 3 publications

References 26 publications

Voltammetric Study of Lomefloxacin Transfer at the Interface between Two Immiscible Electrolyte Solutions: Ionic Partition, Photodegradation, and Sensing Applications

Voltammetric Study of Lomefloxacin Transfer at the Interface between Two Immiscible Electrolyte Solutions: Ionic Partition, Photodegradation, and Sensing Applications

Genetic Diversity and Population Genetic Structure of Korean Black Scraper Thamnaconus modestus in Korea and Japan Based on the mtDNA Marker

Changes in growth, morphology, and levels of digestive enzymes and growth-related hormones in early ontogeny of black scraper, Thamnaconus modestus

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