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Abstract

Various extracts of Ailanthus excelsa bark evaluated for antifungal at a dose 1 mg/ml, anti-inflammatory and analgesic activity at a dose 200 mg/kg and 50 mg/kg of body weight. The experimental methods were used cup plate method for antifungal and formalin induced rat hind paw oedema measured by plethysmograph (mercury displacement method) for anti-inflammatory and Tail flick method for analgesic activity. Flucanazole (1 mg/ml), diclofenac sodium (200 mg/kg, orally) and Novelgin (50 mg/kg, orally) clinically used drugs were used as standards. The ethyl acetate extract showed good antifungal activity against fungal strains A. terrus, A. niger and A. flavus at 1 mg/ml and the remaining extracts showed moderate activity compared to standard flucanzole. Extracts of Ailanthus excelsa bark showed significant antiinflammatory and analgesic activity in the above study.