Untitled

Abstract

The present study was aimed to evaluate the antibacterial potential of the commonly available sea star Protoreaster linckii. The samples were collected from Mandapam, the Gulf of Mannar, southeast coast of India. Four different extracts like methanol, acetonitrile, dichloromethane and ethanol at varying concentrations ranging from 250 to 1000 µg/ml was used for the experiment to study the inhibitory effects on ten selected human urinary tract infectious pathogenic bacteria. A concentration dependent inhibitory effect was observed in all the extracts of star fish. The results of the study suggested that most of the extracts have strong inhibitory activity against different pathogens similar to the standard drugs. Methanolic extracts exhibited a maximum zone of inhibition (17.00±0.1mm) against gram positive Staphylococcus saprophyticus at the higher concentration. Minimum zone of inhibition (0.700±0.35 and 0.800±0.15 mm) were reported in gram positive S. aureus while using the median and higher concentrations of dichloromethane extracts.