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doi:10.13040/ijpsr.0975-8232.9(10).4029-55

Cited by 4 publications

(1 citation statement)

References 125 publications

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“…Green synthesis of nanomaterials using plant extracts as a furious source of natural compounds like carbohydrates, phenolics, flavonoids, tannins, and alkaloids [9,10] that could act as safe reducing and stabilizing agents in addition to their ability to maintaining aseptic environments throughout the process [11,12]. Therefore, medicinal plants of therapeutic potential could control the dimensions and forms of the biosynthesized nanomaterial [13,14].…”

Section: Introductionmentioning

confidence: 99%

The Antimicrobial, Antioxidant, and Anticancer Activity of Greenly Synthesized Selenium and Zinc Composite Nanoparticles Using Ephedra aphylla Extract

et al. 2021

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The current work aimed to synthesize selenium and zinc nanoparticles using the aqueous extract of Ephedra aphylla as a valuable medicinal plant. The prepared nanoparticles were characterized by TEM, zeta potential, and changes in the phytochemical constituents. Hence, the phenolic, flavonoid, and tannin contents were reduced in the case of the prepared samples of nanoparticles than the original values in the aqueous extract. The prepared extract of Ephedra aphylla and its selenium and zinc nanoparticles showed high potency as antioxidant agents as a result of the DPPH• assay. The samples were assessed as anticancer agents against six tumor cells and a normal lung fibroblast (WI-38) cell line. The selenium nanoparticles of Ephedra aphylla extract revealed very strong cytotoxicity against HePG-2 cells (inhibitory concentration (IC50) = 7.56 ± 0.6 µg/mL), HCT-116 cells (IC50 = 10.02 ± 0.9 µg/mL), and HeLa cells (IC50 = 9.23 ± 0.8 µg/mL). The samples were evaluated as antimicrobial agents against bacterial and fungal strains. Thus, selenium nanoparticles showed potent activities against Gram-negative strains (Salmonella typhimurium, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli), Gram-positive strains (Bacillus cereus, Listeria monocytogenes, Staphylococcus aureus, and Staphylococcus epidermidis), and the fungal strain Candida albicans. In conclusion, the preparation of nanoparticles of either selenium or zinc is crucial for improved biological characteristics.

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Section: Introductionmentioning

confidence: 99%

The Antimicrobial, Antioxidant, and Anticancer Activity of Greenly Synthesized Selenium and Zinc Composite Nanoparticles Using Ephedra aphylla Extract

et al. 2021

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Potential Applications of Greener Synthesized Silver and Gold Nanoparticles in Medicine

Noah

2020

Nanoparticles and Their Biomedical Applications

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Yeşil sentez yoluyla mikrosistemlerde çinko oksit nanopartiküllerin üretimi ve karakterizasyonu

Akay¹,

Sefaoğlu²

2021

Gümüşhane Üniversitesi Fen Bilimleri Enstitüsü Dergisi

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Nanoparticles (NP), which can be produced for many different fields and purposes; are at size vary from nanometer to a micrometer. These particles can be prepared by different approaches such as chemical, physical and biological methods. However, the biological approach is the most promising approach among other methods due to its simplicity and environmentally friendly conditions. The production of the nanoparticle by means of a biological approach does not require any high temperature, acidic/basic conditions and hazardous chemicals. Therefore, this method is named "green synthesis". Development in microtechnology has had profound effects in many areas such as drug discovery, biology, diagnosis, and tissue engineering. Microfluidics which focuses on the processing of liquids in microscale systems has attracted wide attention in the production process of nanoparticles due to precise control and fast mixing. The main purpose of this study is to produce and characterize metal nanoparticles by combining microsystems and green synthesis approaches. For this purpose, in the first step, the design of microsystems that suitable for the flow of different phases was performed. In the second step, ZnO nanoparticle synthesis was carried out using the red cabbage (Brassica oleracea var.capitata f. Rubra) extracts. The synthesis of nanoparticles achieved by optimizing different parameters such as; extract: zinc ratio, zinc solution concentration, flow rates, and flow rates ratio in the microsystem and temperature. The results showed that the herbal red cabbage components can be used for the green synthesis of ZnO nanoparticles.

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Cited by 4 publications

References 125 publications

The Antimicrobial, Antioxidant, and Anticancer Activity of Greenly Synthesized Selenium and Zinc Composite Nanoparticles Using Ephedra aphylla Extract

The Antimicrobial, Antioxidant, and Anticancer Activity of Greenly Synthesized Selenium and Zinc Composite Nanoparticles Using Ephedra aphylla Extract

Potential Applications of Greener Synthesized Silver and Gold Nanoparticles in Medicine

Yeşil sentez yoluyla mikrosistemlerde çinko oksit nanopartiküllerin üretimi ve karakterizasyonu

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