Untitled

doi:10.13040/ijpsr.0975-8232.8(12).4909-29

Cited by 2 publications

(1 citation statement)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Finally, spectroscopic characterization by 13 C NMR shows chemical shifts for the benzothiazole without substituents at 155 ppm (C2), 123 pm (C4), 126 ppm (C5), 125 ppm (C6), 122 ppm (C7), 153 ppm (C3a) and 134 ppm (C7a). Ultraviolet-visible spectroscopy (UV-Vis) shows a more complex electronic absorption with λ max of 217, 251 nm, (ε = 18,620 L mol −1 cm −1 , 5500 L mol −1 cm −1 ), 285 nm (ε = 1700 L mol −1 cm −1 ) and 295 nm (ε = 1350 L mol −1 cm −1 ) [60][61][62].…”

Section: Synthesis and Characterization Of Benzothiazolesmentioning

confidence: 99%

Copper-Coordinated Thiazoles and Benzothiazoles: A Perfect Alliance in the Search for Compounds with Antibacterial and Antifungal Activity

et al. 2023

View full text Add to dashboard Cite

Throughout human history, bacteria and fungi have caused infections that are difficult to combat. For this reason, countless research groups have developed novel compounds to solve this problem. Thiazole and benzothiazole are present in different structures with interesting biological effects and are used to develop new effective antimicrobial agents. Moreover, nitrogen atoms that are present in this heterocycle allow for coordination with various metals, forming metal complexes that enhance the biological activity of organic ligands that are often used as commercial drugs. This bibliographical review summarizes the copper complexes that use thiazole and benzothiazole as ligands and that report efficient antimicrobial activity against different bacteria and fungi.

show abstract

Section: Synthesis and Characterization Of Benzothiazolesmentioning

confidence: 99%

Copper-Coordinated Thiazoles and Benzothiazoles: A Perfect Alliance in the Search for Compounds with Antibacterial and Antifungal Activity

et al. 2023

View full text Add to dashboard Cite

show abstract

Recent Insights on Synthetic Methods and Pharmacological Potential in Relation with Structure of Benzothiazoles

Yadav

Kumar

Singh

et al. 2023

View full text Add to dashboard Cite

Benzothiazole is a bicyclic heterocyclic compound that contains benzene fused with 1, 3-thiazole ring. Several researches established the potential of benzothiazoles as important moiety in various adverse pharmacological conditions. Benzothiazole and its derivatives have been in use and marketed as anti-microbial, anti-inflammatory, anti-diabetic, anti-oxidant, anti-convulsant, anti-tumor, etc. The variations in pharmacological potentials of the benzothiazole and its derivatives have been in rational with their chemical structure. Nowadays, hybridization of two or more pharmacophore to synthesize a single molecule with potent pharmacological action is used. This helps to synergize pharmacological properties, make interaction possible with many targets, or minimize the adverse effects associated with them. Several synthetic approaches have been reported for benzothiazole and its derivatives. In this present review, we focused on recently adopted synthetic approaches for the synthesis of the benzothiazole nucleus and its derivatives. The structure-activity relationship in relation with different pharmacological activities has also been highlighted to provide a good understanding to the researchers for future research on benzothiazoles.

show abstract

Untitled

Cited by 2 publications

References 27 publications

Copper-Coordinated Thiazoles and Benzothiazoles: A Perfect Alliance in the Search for Compounds with Antibacterial and Antifungal Activity

Copper-Coordinated Thiazoles and Benzothiazoles: A Perfect Alliance in the Search for Compounds with Antibacterial and Antifungal Activity

Recent Insights on Synthetic Methods and Pharmacological Potential in Relation with Structure of Benzothiazoles

Contact Info

Product

Resources

About