Abstract:Depression is a chronic, recurring, and potentially lifethreatening illness. The present work is to formulate floating tablets of venlafaxine hydrochloride as this drug is used to treat depression. GIT absorption of venlafaxine hydrochloride is poor due to low aqueous solubility. Thus, an attempt was made to enhance it gastric residence time that will improve its dissolution profile. The floating tablets were prepared by direct compression method. The Fourier transform infrared spectroscopy revealed absence of… Show more
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