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Abstract

Present study highlights that plant as a source of medicine has been inherited and is an important component of the health care system in India. Ziziphus mauritiana fruit (Rhamnaceae), one of the medicinally important plants commonly found in subtropical countries, was chromatographically evaluated in the present work for the identification of various phytochemical compounds found in it. The phytochemical tests showed the presence of alkaloids, flavonoids, phenols, saponins, tannins in methanolic extract of Ziziphus mauritiana (MEZM). Majorly 24 compounds in 93.08% peak area were identified through spectrum matching with National Institute Standard and Technology (NIST) database. In accordance with known therapeutic effects of the identified compounds like 5-Hydroxymethyl furfural; 1, 5-Anhydroglucitrol; Polygalitol; Sedoheptulosan; D-Allose; Beta-D-Glucopyranoside Methyl; 3, 4-Altrosan; Nonanoic acid; Octanoic acid; 2-Hexyl-2-Hexadecanoic acid; 2-Propyloctanoic acid; Molinate; Levetriracetam; Clindamycin and Maltol, the MEZM fruit's justified a very good source of therapeutic agents for Cancer, Epilepsy, Alzheimer's disease, Parkinson disease, Amyotrophic Lateral Sclerosis (ALS), bacterial and fungal infections. Also, it is rich in compounds comprising anti-oxidant, anti-spermatogenic, antibiotic , neuroprotective activity. Moreover, carbohydrate metabolism and total cholesterol regulatory compounds were also identified. Therefore, Z. maurtiana is found a pharmacologically important plant. Further, isolation of individual phytochemical constituents and subjecting it to the biological activity will give more pharmaceutically valuable results.

ANTIBACTERIAL AND ANTIBIOFILM ACTIVITIES OF Swietenia macrophylla King ETHANOLIC EXTRACT AGAINST FOODBORNE PATHOGENS

“…In the present study, 3,4-Altrosan (1.44%) was identified in SMEE. This finding is in line with Kushwaha et al (2019) demonstrating that 3, 4-Altrosan (6.92%) was a major component of methanolic extract of Ziziphus mauritiana fruit.…”

Indian jujube a potential fruit tree to improve the livelihood

“… Zizyberenalic acid( Karim et al, 2019 ) Pentacyclic triterpenoid Cytotoxic activity( Lee et al, 2003 ). 5-Hydroxymethylfurfural( Kushwaha et a., 2019 ) Furan derivative Antioxidant, anticancer activity & antiproliferative activity ( Zhao et al, 2013 ). D-Allose( Kushwaha et a., 2019 ) Aldohexose sugar Immunosuppressant on allogenic orthotopic liver transplantation( Hirooka et al, 2006 ),Anti-cancerous( Mitani et al, 2009 ),Suppresses ROS production in the mitochondria( Ishihara et al, 2011 ),Neuroprotective effects( Liu et al, 2014 ).…”

“… 5-Hydroxymethylfurfural( Kushwaha et a., 2019 ) Furan derivative Antioxidant, anticancer activity & antiproliferative activity ( Zhao et al, 2013 ). D-Allose( Kushwaha et a., 2019 ) Aldohexose sugar Immunosuppressant on allogenic orthotopic liver transplantation( Hirooka et al, 2006 ),Anti-cancerous( Mitani et al, 2009 ),Suppresses ROS production in the mitochondria( Ishihara et al, 2011 ),Neuroprotective effects( Liu et al, 2014 ). Naringenin( Memon et al, 2012 ) Flavonoid Antioxidant, antitumor, antibacterial, anti-inflammatory( Salehi et al, 2019 ) Quercetin 3′-O-glucoside( Memon et al, 2013 ) Flavonoid Antidiabetic and antioxidative effects( Panda & Kar, 2007 ) Rutin( Yahia et al, 2020 ) Flavonoid glycoside Antioxidant, and cardio protective activities( Ganeshpurkar and Saluja, 2017 ) Quinic acid( Soraya et al, 2022 ) Phenol Antioxidant and analgesic effects( Benali et al, 2022 ) Hexadecanoic acid( Soraya et al, 2022 ) Long-chain fatty acid Antioxidant, antimicrobial, anti-inflammatory hypocholesterolemia, Nematicide,&Antiandrogenic ( Sheela, &Uthayakumari, 2013 ) Seed Ceanothic acid( Guo et al, 2014 ) Triterpenoid Cytotoxic effect( Lee et al, 1998 ) Betulinic acid( Guo et al, 2014 ) Pentacyclictriterpenoid Anti-HIV, anti-bacterial, anti-malarial, and anticancer activities ( …”

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“…HPLC analysis of methanol extract of its fruit pulp showed the presence of predominant flavonoids such as rutin, myricetin, and apigenin 20 . Non-volatile compounds were identified in the methanol extract of fruit by GC-MS, the most abundant was5hydroxymethylfurfural 21 . The fruit pulp of Z. mauritiana is several pharmacological properties, including antioxidant 22,23 anticancer 24 , antiinflammatory 24 , anti-bacterial 25 and anti-diarrhoeal 26 .…”