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Rao, Srinivas K; Sudhir, Rachapalli R.; Fogla, Rajesh; Rajagopal, Rama; Sitalakshmi, G; Padmanabhan, Prema

doi:10.1023/a:1010635231828

Cited by 16 publications

(3 citation statements)

References 11 publications

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“…Also, keratoconus is the indication for corneal transplantation in about 7-10% of Indian subjects. [11] It is estimated that at the national level, we are able to procure only about 10% of required number of corneas (National Workshop on Corneal Blindness and Eye Banking, 2005). If Intacs are able to take care of a certain percentage of patients with advanced keratoconus, it will help reduce the burden of donor corneal requirement.…”

Section: Discussionmentioning

confidence: 99%

Safety and efficacy of Intacs in Indian eyes with keratoconus: An initial report

Shetty

Narayana

Mathew

et al. 2009

Indian J Ophthalmol

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ContextIn contact lens-intolerant keratoconus patients, intrastromal placement of Intacs is becoming a promising new modality of treatment.AimsTo study the safety and efficacy of implantation of microthin corneal inserts (Intacs) in Asian-Indian keratoconus patients.Settings and DesignRetrospective interventional case series, in the cornea and refractive surgery service, at a tertiary care eye hospital in South India, between May 2006 and July 2007.Materials and MethodsIntacs (Addition Technology, USA) were successfully implanted by mechanically creating tunnels, in 12 eyes of 12 keratoconus patients, who were contact lens-intolerant. The patients (mean age 25.58 years, nine male and three female) had a minimum follow-up of six months. Five patients had severe keratoconus (mean K > 53 D) and nine had central cones.ResultsAll patients improved or retained visual acuity. The uncorrected visual acuity (UCVA) improved from a mean value of 0.06, (SD ± 0.08) to 0.19 postoperatively (SD± 0.15) (P= 0.01). The change in mean best corrected visual acuity (BCVA) was from 0.51, (SD ± 0.24), to 0.69, (SD ±0.00) (P = 0.01) postoperatively. The average central keratometry reading was 52.55 D. The change in mean K from 52.84 to 49.16 and 49.15 at one and six months respectively, was statistically significant. We did not have any major intra- or early postoperative complications. Eight of 12 eyes became contact lens-tolerant post-surgery.ConclusionThe procedure of Intacs implantation appears to be safe and effective in a small group of Indian population at an intermediate follow-up.

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Section: Discussionmentioning

confidence: 99%

Safety and efficacy of Intacs in Indian eyes with keratoconus: An initial report

Shetty

Narayana

Mathew

et al. 2009

Indian J Ophthalmol

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“…Ceratocone 24 (38,7) Distrofias corneanas [31][32][33][34][35][36][37] 07 (11,3) Ceratopatia bolhosa pseudofácica/afácica 15,[38][39][40][41][42]49 07 (11,3) Cicatriz corneana [43][44][45][46][47] 05 (8,1) Ceratite infecciosa [52][53][54][55] 04 (6,5) Leucoma [56][57][58][59] 04 (6,5) Ceratopatia bolhosa 48,50,51 03 (4,8) Lesões ulcerativas [60][61][62] 03 (4,8) Retransplante 63,64 02 (3,2) Trauma 65,66 02 (3,2) Ceratite corneana pelo vírus Herpes Simplex 9 01 (1,6) Indicações por países (IDH**) Países com IDH muito alto 5 Ceratocone 9,10, [13][14][15]17,23,25,26,[28][29]…”

Section: Indicações Clínicas N* (%) Causas Geraisunclassified

“…Em relação às distrofi as corneanas, também foi destacada como uma das principais causas gerais do transplante de córneas [31][32][33][34][35][36][37] e em países com IDH muito alto [32][33][34][35][36][37] . Estudos retrospectivos 68,69 apresentaram alta prevalência das indicações do transplante de córneas proveniente dessa causa, principalmente os realizados por técnicas lamelares, além de apontar o envelhecimento populacional como principal fator para o progressivo aumento na incidência de distrofi as corneanas, por se tratar de uma condição que afeta grande parte da população idosa.…”

Section: Indicações Clínicas N* (%) Causas Geraisunclassified

Indicações Clínicas para o Transplante Corneano no Contexto Global: Revisão Integrativa

Cardoso¹,

Júnior²,

Manvailer³

et al. 2022

SDH

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Objetivo: Descrever as principais indicações clínicas para ceratoplastia de acordo com o Índice de Desenvolvimento Humano (IDH) dos países estudados.Materiais e Métodos: Trata-se de uma revisão integrativa de literatura realizada em cinco bases de dados relevantes na área da saúde. A amostra final foi composta por 58 artigos, recuperados das bases: SCOPUS, PubMed Central/MEDLINE, Science Direct, Web of Science e Cumulative Index to Nursing and Allied Health Literature (CINAHL), os quais foram analisados de forma descritiva.Resultados: Das indicações gerais, os estudos apontaram ceratocone (38,7%) como a mais comum, assim como em países com IDH muito alto (22.6%) e países com IDH alto (12,9%) e a ceratite infecciosa em países com IDH médio.Conclusão: As principais indicações para ceratoplastia foram o ceratocone, tanto em países com IDH muito alto quanto alto e a ceratite infecciosa em países com IDH médio. Destacou-se a maior frequência de indicações de causas infecciosas em países com IDH médio devido às fragilidades dos sistemas de saúde para lidar com causa evitáveis, e salienta a necessidade de estratégias para atenção à saúde, diagnóstico precoce e medidas preventivas.

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Clinical outcome of sequential bilateral pediatric penetrating keratoplasty (PKP) in patients with corneal dystrophies in South India

Gyanchand,

Mamatha,

Tabani

et al. 2024

Advances in Ophthalmology Practice and Research

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Abstract: Bilateral penetrating keratoplasty has reasonable success in selected patients. Corneal transplantation in the second eye does not seem to increase the risk of graft rejection in either eye.

Cited by 16 publications

References 11 publications

Safety and efficacy of Intacs in Indian eyes with keratoconus: An initial report

Safety and efficacy of Intacs in Indian eyes with keratoconus: An initial report

Indicações Clínicas para o Transplante Corneano no Contexto Global: Revisão Integrativa

Clinical outcome of sequential bilateral pediatric penetrating keratoplasty (PKP) in patients with corneal dystrophies in South India

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