Untitled

Yost, Kathleen J.; Perkins, Carin; Cohen, Richard. D.; Morris, Cyllene R.; Wright, William E.

doi:10.1023/a:1011240019516

Cited by 808 publications

(410 citation statements)

References 24 publications

Supporting

Mentioning

370

Contrasting

Order By: Relevance

“…The CCR does not collect data on individual‐level measures of socioeconomic status (SES). A previously described composite measure was used to assign each case to a quintile of neighborhood SES (nSES) based on the Census block group of the geocoded address at the time of diagnosis 5, 6…”

Section: Methodsmentioning

confidence: 99%

Racial disparities in outcomes for high‐grade uterine cancer: A California cancer registry study

et al. 2018

View full text Add to dashboard Cite

BackgroundEndometrial cancer (EC) is the most common gynecologic malignancy. We examined factors affecting overall prognosis and survival among different racial groups diagnosed with high‐grade EC.MethodsWe utilized the California Cancer Registry database (CCR) to identify women with high‐grade II EC from 1998 to 2009. Using the Kaplan‐Meier method, we described disease‐specific survival. Survival by stage, race, and time to treatment category was compared using the log‐rank test. The associations of race with disease‐specific survival were modeled using Cox proportional hazards regression. Covariates were selected a priori.ResultsA total of 10 647 patients met study eligibility criteria. The majority of patients in this cohort of high‐grade EC were non‐Hispanic (NH) white (64.1%), followed by Hispanic (15.7%), Asian (10.4%), and NH black (9.8%). NH black women had higher incidence of certain aggressive histologic subtypes in comparison with NH whites, including serous carcinomas and carcinosarcoma.Non‐Hispanic black patients had a worse 5‐year disease‐specific survival (DSS) when compared to other racial groups. The five‐year DSS for NH black women was 54% (51%‐57%), compared to NH white women 66% (65%‐67%), Hispanic 67% (64%‐69%), and Asians 69% (67%‐72%) (P < 0.0001). This clear survival disadvantage of NH black women persisted when controlling for other factors.ConclusionsNon‐Hispanic black women have a higher incidence of more aggressive histologic subtypes even among a cohort of women high‐grade EC and have a disproportionately worse disease‐specific survival after controlling for factors such as age, histologic subtype, stage, time to treatment, and type of treatment.

show abstract

Section: Methodsmentioning

confidence: 99%

Racial disparities in outcomes for high‐grade uterine cancer: A California cancer registry study

et al. 2018

View full text Add to dashboard Cite

show abstract

“…We decided to adjust for these confounders and additionally for other potential confounders that were a major risk factor (30% increased risk) for breast cancer and were found to be differentially associated with shift work. The final adjustment set therefore was: age (1,11,12), ethnicity (1,13,14), socioeconomic status (or a proxy) (10,(15)(16)(17), parity (16,(18)(19)(20)(21) with adjustment done for either number of children, or age at first child, and body mass index (BMI) (overweight, obese) (22)(23)(24).…”

Section: Confoundersmentioning

confidence: 99%

Night-shift work and breast cancer – a systematic review and meta-analysis

Ijaz¹,

Verbeek²,

Seidler³

et al. 2013

Scand J Work Environ Health

205

139

View full text Add to dashboard Cite

show abstract

“…Quintile of SES was derived from a principle component analysis using data from the 2000 U.S. census [39]. SES was assigned at the census block group level and based on address at time of initial diagnosis as reported in the medical record.…”

Section: Variablesmentioning

confidence: 99%

Tumor marker phenotype concordance in second primary breast cancer, California, 1999–2004

Brown

Bauer

Pare

2009

Breast Cancer Res Treat

View full text Add to dashboard Cite

Breast cancer is the most common cancer among women. It is estimated that 7% of women who have breast cancer will develop a subsequent second independent breast tumor within 10 years of the first. The status of estrogen (ER), progesterone (PR) and human growth hormone (HER2) receptors, individually and as phenotypic combinations, impacts the clinical course of breast cancer and may impact the course of subsequent primary tumors and patient survival. Our aims were to determine tumor marker phenotype concordance between first and second primary breast cancers (FPBC and SPBC), describe demographic and clinical characteristics, and examine first tumor treatments associated with phenotype concordance. A total of 76,209 cases of female invasive breast cancer were identified in the California Cancer Registry from 1999 to 2004. Of those, 1,407 women who had not undergone a prophylactic mastectomy, had information on the status of three tumor markers, and were diagnosed with an SPBC during the study period were selected. SPBCs were significantly smaller, diagnosed at a higher stage and were node positive. Patients whose FPBC was ER(+)/-/PR(+)/-/HER2- and triple negative (TN) (ER-/PR-/HER2-), often had concordant phenotypes for their SPBC. ER(+)/-/PR(+)/-/HER2+ and HER2-positive (ER-/PR-/HER2+) FPBCs, often had discordant phenotypes for their SPBC. ER(+)/-/PR(+)/-/HER2- SPBCs often lacked HER2 expression and were ER and/or PR positive. Tumor laterality and synchronicity significantly predicted concordance as did having a FPBC whose phenotypes were ER(+)/-/PR(+)/-/HER2+, HER2-positive and TN, while first primary tumor treatment with chemotherapy predicted discordance. The relationship between multiple primary breast cancer phenotype concordance and patient prognosis has yet to be determined. Our results indicate that SPBC surveillance strategies include consideration of FPBC phenotype. Although our results are provocative, they may have been influenced by current criteria used to determine tumor independence.

show abstract

Untitled

Abstract: Our results are consistent with similar findings for the Los Angeles area but differ from previous results for the San Francisco Bay area.

Cited by 808 publications

References 24 publications

Racial disparities in outcomes for high‐grade uterine cancer: A California cancer registry study

Racial disparities in outcomes for high‐grade uterine cancer: A California cancer registry study

Night-shift work and breast cancer – a systematic review and meta-analysis

Tumor marker phenotype concordance in second primary breast cancer, California, 1999–2004

Contact Info

Product

Resources

About