973-P: The Feasibility of Continuous Glucose Monitoring in Youth with Type 2 Diabetes Mellitus: A Pilot Study

Abstract

Background: Continuous glucose monitoring (CGM) systems are increasing in use among youth with type 1 diabetes; however, the feasibility of wearing an unblinded, real-time CGM has not been studied in youth with type 2 diabetes. The aims of this study are to evaluate the feasibility of CGM and to explore its effects on lifestyle behaviors and glycemic control among youth with type 2 diabetes. Methods: Youth ages 12-19 years (n=17) with type 2 diabetes participated in a prospective cohort intervention study with Dexcom G6 CGM. For baseline data, participants wore a blinded CGM for the 1st week and unblinded CGM for the 2nd and 6th weeks. Glycemic and metabolic measures (glucose, insulin, c-peptide, hemoglobin A1C, fructosamine, 1,5 anhydroglucitol, lipids), 24-hour food recalls, and Youth Eating Disorder Questionnaires (YEDE-Q) were collected at baseline and conclusion of study. Results: Eight participants have completed the study to date (4F/4M, mean age 15.7 years, BMI mean 32.6 kg/m2); data on metabolic measures, food recall, YEDE-Q are pending. See Table 1. Conclusion: Based on this pilot study, CGM use among youth with type 2 diabetes is feasible and acceptable. Larger studies of longer duration are needed to demonstrate whether real-time CGM can improve glycemic control and lifestyle behaviors in this population. Disclosure A. LaRoche: None. K. Utzschneider: Consultant; Self; Novo Nordisk Inc. C. Pihoker: None. Funding National Institutes of Health (DK007247)