Abstract:BackgroundRenal involvement in systemic lupus erythematosus (SLE) is associated with high morbidity and mortality. Current standard tools to monitor lupus nephritis (LN) are suboptimal compared to the invasive renal biopsy. The renal activity index in lupus (RAIL) was developed using 6 urinary biomarkers to reflect disease activity. In children this tool was 92% accurate in identifying active LN. We aim to study the changes in this score in relation to induction treatment in LN.MethodsUrine samples were collec… Show more
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