941-17 Left Atrial Booster Pump Function in Patients with Ischemic Cardiomyopathy and Idiopathic Dilated Cardiomyopathy

Wang, Yuepeng; Takenaka, Katsu; Kuwada, Yukihiro; Sonoda, Makoto; Igarashi, Tsutomu; Watanabe, Fumiyoshi; Omata, Masao

doi:10.1016/0735-1097(95)92140-z

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“…These findings suggested that atrial fibrosis in these patients may not have been related to mechanical overload of the left atrium but rather to LA involvement in the myopathic process [5] . These findings were further emphasized in a number of observational studies that reported LA contractile dysfunction in DCM and preservation in ischemic cardiomyopathy (ICM) [4] , [6] , [7] .…”

Section: Introductionmentioning

confidence: 84%

Left atrial geometry and pump function in ischemic cardiomyopathy

Abdelghani

Atteia

2014

IJC Heart & Vasculature

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BackgroundMany of the factors that are known to alter left atrial (LA) contractility are present in patients with ischemic cardiomyopathy (ICM). Nevertheless, preservation of LA contractile function in this group of patients was reported in previous studies. The aim of this study was to assess the changes in LA size, geometry and contractile function in ICM.Methods and results60 subjects (age: 49 ± 12 years, 53% males) in sinus rhythm undergoing coronary angiography (CA), were enrolled in this study; 15 subjects as a control group, 30 patients with reduced ejection fraction (EF) and significant coronary artery disease; as the ICM group, and 15 with reduced EF and normal CA; as the dilated cardiomyopathy (DCM) group.LA dimensions, volume, active emptying fraction (ACTEF) and eccentricity index (LAEi) as well as late diastolic velocities of the mitral annulus (a′) and LA free wall (A3) were measured.Compared with the control group, ICM patients had larger LA volume and reduced ACTEF, a′ and A3, with no significant difference between patients with ICM and DCM in any of these parameters. LA eccentricity was, non-significantly, higher in both cardiomyopathy groups than in the control group.ConclusionsPatients with ICM have increased LA volume and reduced LA contractile function in comparison with normal controls. LA enlargement, LA contractile dysfunction and LA geometric changes in ICM are similar to that occurring in DCM. LA size, contractile function and eccentricity may not be reliable in differentiating ischemic from idiopathic dilated cardiomyopathy.

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