92074139 Menopausal hormone replacement therapy and breast cancer: A meta-analysis

Sillero-Arenas, Marı́a; Delgado-Rodriquez, M; Rodigues-Canteras, R; Bueno‐Cavanillas, Aurora; Gálvez-Vargas, Ramón

doi:10.1016/0378-5122(92)90108-g

Cited by 4 publications

(9 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Indeed,ifwereconsider the meta-analysisb yS illero-Arenase ta l. [1]a nd uset he appropriatet ools in as econdary analysis, we find an estimate of 1.137onthe relative risk scale. This finding occurs sincet he meta-analysisathandexperiences considerable unobservedh eterogeneity, whichh as previouslyb een ignored (leading to ad i-minishedeffect estimate of 1.06).…”

Section: Methodsinf Med1/2005mentioning

confidence: 92%

“…[1]-t hroughout thisp aper abbreviateda s SA -and point out that the finding of the recenttrial [2] is not surprising andessentially agrees with the result of the meta-analysis. Them eta-analysis [1] contained2 3c asecontrol studies and13cohortstudies. There wasalsoone clinical trialmentioned thatis not further consideredh eres incer elevant information could not be retrievedf or this study.…”

Section: An Application: Thedataof Themeta-analysisofhormone Replacemmentioning

confidence: 99%

“…AnalysisbySillero-Arenas et al [1] We nowc ome back to the MA of SA and applythe ideasofsection 3. The homogeneity model showsconsiderabledifferenceto the heterogeneity model (see Table4).…”

Section: Reanalysisofthe Meta-mentioning

confidence: 99%

See 2 more Smart Citations

Meta-Analysis

Böhning¹

2005

Methods Inf Med

View full text Add to dashboard Cite

The topic of HRT and breast cancer has again very recently become an issue of public debate, when results of a large trial investigating the health effects of hormone replacement therapy were published indicating an increased risk for breast cancer (risk ratio of 1.26). Using an adequate regression model in the previously published meta-analysis an adjusted estimate of effect of 1.14 can be given which is considerably higher than the one published in the meta-analysis of Sillero-Arenas et al. In summary, it is hoped that the method suggested here contributes further to a good meta-analytic practice in public health and clinical disciplines.

show abstract

Section: Methodsinf Med1/2005mentioning

confidence: 92%

Section: An Application: Thedataof Themeta-analysisofhormone Replacemmentioning

confidence: 99%

See 1 more Smart Citation

Meta-Analysis

Böhning¹

2005

Methods Inf Med

View full text Add to dashboard Cite

show abstract

“…Nevertheless, metaanalyses do expose significant trends and the findings of three are shown in Table l. 23 • 25 These indicate there is insufficient evidence to confirm or refute an association between short-term ( <5 years) use of unopposed oestrogen and risk of breast cancer. Two of the overviews found a small increase in overall risk of developing breast cancer in women who had ever taken H~T, but in only one was the relative risk of 1.06 statistically significant.…”

Section: Exogenous Hormone Replacement and Breast Cancer -mentioning

confidence: 99%

Hormone Replacement Therapy and Breast Cancer

Faiz

Fentiman

1998

Int J Clinical Practice

View full text Add to dashboard Cite

SUMMARYHormone replacement therapy (HRT) leads to a similar annual increase in risk of breast cancer as does each extra year of remaining premenopausal. Taken for more than 10 years HRT leads to a 35% increase in risk of developing breast cancer. It does not increase a woman's risk of dying of breast cancer, and may improve the prognosis. Some breast cancer patients can safely take HRT and some formulations might reduce the subsequent risk of relapse.

show abstract

“…Surg. -November 1998 data must be interpreted with caution because of the way the study was performed. Pregnancies were identified by a registry of live births.…”

Section: Pregnancymentioning

confidence: 99%