9-Acridone insect antifeedant alkaloids from Teclea trichocarpa bark

Abstract

Three 9-acridone alkaloids, melicopicine, tecleanthine and 6-methoxy tecleanthine were isolated from the bark of Teclea trichocarpa. Melicopicine and tecleanthine exhibited mild antifeedant activity against the African armyworm, Spodoptera exempta. All the three alkaloids showed antimicrobial activity against the fungus, Cladosporium cucumerinum and the bacterium, Bacillus subtilis.

Acridone alkaloids with cytotoxic and antimalarial activities from Zanthoxylum simullans Hance

“…[12] It is noteworthy to mention that all these acridone alkaloids were isolated from this plant for the first time.…”

The cyclobuta[b]quinoline alkaloid cyclomegistine from Teclea gerrardii I.Verd. (Toddalioideae: Rutaceae)

“…H.Perrier (Vaquette et al, 1974), and, more recently, T. trichocarpa Engl. collected in Kenya (Lwande et al, 1983;Muriithi et al, 2002).…”

Botanical Pesticides

“…Three 9-acridone alkaloids isolated from Teclea trichocarpa Eng. bark have been shown to deter feeding by the beet armyworm (50). The alkaloid N-methylflindersine and several benz(C)-phenanthridine alkaloids obtained from the East African root bark of Fagara chalybea Engl, and F. holstii F. deterred feeding by beet armyworm and the Mexican bean beetle (51).…”