822 Decreased Numbers of T Cells and Subpopulations, Increased Mitogen Reactivity and Defective Immunoglobulin Synthesis in Acute Lymphoblastic Leukemia in Long Term Remission
Abstract:; (spon. by S. Inoue), Children's Hospital of Michigan (CHI), Detroit, Michigan 48201.Recent reports have indicated that elevated CSF levels of B2m in AL patients may precede the cytologic diagnosis of central nervous system (CNS) involvement. This prompted us to reevaluate the CSF B m levels obtained on 42 AL patients at CHM during the years [1972][1973][1974][1975]. All but 3 had acute lymphoblastic leukemia (ALL) 36 ALL children were receiving CNS prophylaxis consisting of intrathecal (IT) Methotrexate (MTX… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.