Abstract:Intranasal delivery of EVs represents a feasible approach to treat perinatal brain damage by effectively delivering EVs to the brain while bypassing the systemic circulation. Intranasal delivery of EVs could also be suitable to treat other preterm-associated complications such as bronchopulmonary dysplasia and severe necrotizing enterocolitis as it was shown that a fraction of EVs also reached the lungs and the GI tract. Financial support by Gottfried and Julia Bangerter-Rhyner Foundation.
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