79 Congestive heart failure, atrial fibrillation, chronic RV-pacing and cardiac resynchronization therapy

Abstract

Purpose: Cardiac Resynchronization Therapy (CRT) is currently being targeted to moderately and severely symptomatic heart failure patients (NYHA Class Ill and IV), with systolic dysfunction (Ejection fraction <35%) and evidences of ventricular dyssynchrony (QRS > 130ms). Aim of the study was to assess the effects of CRT in mildly symptomatic patients (NYHA Class II) with respect to patients with standard indications.Methods: 1232 patients (684-9 years, 1010 male, 569 ischemic) were enrolled in the InSync/InSync ICD Italian Registries and followed for 164-14 months. At baseline, 235 patients were classified in NYHA Class II (654-10 years, 1.74-1.0 hospitalizations for heart failure in the 12 months preceding the implant with a mean number of 9.34-7.8 days of hospitalization), the remaining 997 were in NYItA Class llI or IV (684-9* years, 2.34-1.4" hospitalizations with 22.24-17.1" days of hospitalization). *p<0.001 versus NYHA Class II.