753 Age Is Not a Contraindication for an Orthotopic Ileal Neobladder Following Radical Cystectomy

Improving selection of appropriate urinary diversion following radical cystectomy for bladder cancer

“…Although it is generally believed that patients younger than 70 years of age may have better continence, this has not been corroborated in recent studies [35,36]. In our recent study of 111 neobladder patients of whom 40 (29%) were 70 years or older, we found no significant association between age and day-or night-time continence [37]. Similarly, measurement of performance status cannot be generalized and has to be assessed individually in every patient.…”

“…Nighttime incontinence is generally higher, ranging between 20 and 30% [21,46]. The risk factors influencing daytime incontinence were age over 65 years, use of colonic segments and in some studies lack of nerve-sparing techniques [46], although in our study continence rates in carefully selected elderly patients were similar to their younger cohorts [37]. The reasons for the higher night-time incontinence rates result from the absence of a neurofeedback loop to the brain, of sphincter-detrusor reflex, as well as decreased rhabdosphincter tone at night.…”