1970
DOI: 10.1097/00003086-197007000-00008
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7 Surgical Management of Tophaceous Gout

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Cited by 27 publications
(17 citation statements)
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“…In this series, the tophaceous masses were cut into small pieces by the rapidly rolling inner cutting blade through the side port of the shaver tip and removed simultaneously by the suction system. Larmon 19 suggests frequent irrigation of the wound during surgery to wash away urate. Because the solubility of urate is markedly temperature-dependent with a twofold increase in solubility between 25°C and 37°C, 7 warm normal saline irrigation is used in this series for lowering the rate of clogging.…”
Section: Discussionmentioning
confidence: 99%
“…In this series, the tophaceous masses were cut into small pieces by the rapidly rolling inner cutting blade through the side port of the shaver tip and removed simultaneously by the suction system. Larmon 19 suggests frequent irrigation of the wound during surgery to wash away urate. Because the solubility of urate is markedly temperature-dependent with a twofold increase in solubility between 25°C and 37°C, 7 warm normal saline irrigation is used in this series for lowering the rate of clogging.…”
Section: Discussionmentioning
confidence: 99%
“…Approximately 5% of patients may not respond to medical management as a result of which some of these cases may progress to the tophaceous stage. 4 When the skin overlying the tophus deposit becomes ulcerated, microorganisms may enter through the ruptured tophaceous wound, resulting in infection. Large or extensive wounds need joint resection or longterm wet dressing to drain the tophus and to achieve healthy granulation tissue coverage of the wound.…”
Section: Discussionmentioning
confidence: 99%
“…The initial radiographic lesions, usually asymmetrical, are characterized by thickening of the soft tissues and large erosions, most frequently located in the ulnar dome, carpal bones, and the base of the metacarpals. The articular spaces are usually preserved for a long time, before destruction is caused by crystal deposits in the hyaline cartilage and synovial membrane, which lead to degeneration and ankylosis (Ludwig et al 1938, Hughes et al 1968, Case report of the Massachussetts General Hospital 1970, Larmon 1970, Watt and Middlemiss 1975, Good and Rapp 1978, Bardin and Fritz 1992, Cortet et al 1994, Resnick et al 1995. The initial carpal lesions may correspond to atraumatic aseptic osteonecrosis, initiated by osseous gouty deposits.…”
Section: Discussionmentioning
confidence: 99%