7: Randomized clinical trial of postoperative belladonna and opium (B&amp;O) suppositories in vaginal surgery

Butler, KA; Yi, Jie; Klauschie, Jennifer; Ryan, Daisy; Hentz, J. G.; Cornella, Jeffrey L.; Magtibay, P.; Kho, Rosanne M.

doi:10.1016/j.ajog.2016.01.016

Cited by 1 publication

(2 citation statements)

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“…13,35,36 According to the literature, it has been proved that rectal route morphine results less analgesia and lower pain scores compared to its IV administration. 34,37 The findings of both groups showed the similarity in the different demographic features including age, gender, weight, 1, P = 0.329). As well, 24 patients (70.6%) in RSM group and 29 patients (80.6%) in IMM group were male and no significant differences were seen in the distribution of sex in two groups (Table 1, P = 0.331).…”

Section: Discussionmentioning

confidence: 77%

“…31 Although, oral and parenteral narcotics are used usually for pain relief in EW or following surgical procedures, these routs can exacerbate the incidence of sedation, vomiting, and nausea, which ultimately delays recovery. [32][33][34] Thus, non-parenteral route of analgesic drugs, especially their rectal route has been suggested in different studies. 13,35,36 According to the literature, it has been proved that rectal route morphine results less analgesia and lower pain scores compared to its IV administration.…”

Section: Discussionmentioning

confidence: 99%

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Comparison of rectal suppository and intramuscular morphine for management of patients with renal colic referred to the emergency department: A randomized double-blinded controlled trial

Zadeh

Moonesan

Taheri

et al. 2023

J. Contemp. Med. Sci.

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Objectives: To compare the analgesic effects of rectal suppository morphine (RSM) with intramuscular morphine (IMM) in patients suffered from renal colic referred to emergency ward (EW). Methods: In a controlled, randomized, clinical trial, 74/90 patients with renal colic referred to the EW between March 2016 and March 2017 were randomly enrolled into two groups of RSM (10 mg) and IMM (10 mg/mL). Vital signs and severity of pain were recorded at admission time (0), 15, 30 and 60 min after treatment. Results: The results showed that there was a significant decrease in VAS score of RSM group compared to IMM group after 30 and 60 min of administration (P˂0.05). Furthermore, no significant difference was recorded in vital signs, except there was a significant decrease in heart rate (15 and 60 min) and respiratory rate (60 min) of RSM group compared to IMM group (P˂0.05) and no side effects were recorded during the investigation. Conclusion: In conclusion, the use of rectal route of morphine had higher efficiency compared to the IM route of morphine in relieving pain of patients with renal colic. Although, decreased heart and respiratory rates were recorded, the values were in normal range. As well, no major complications were recorded for each method.

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