7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidine-4-ylamine, an lck tyrosine kinase inhibitor

Abstract

The molecular and crystal structures of the potent and selective lck tyrosine kinase inhibitor, C23H22N4O, have been determined by single‐crystal X‐ray diffraction. The pyrrolo­pyrimidine and phenyl rings are planar while the cyclo­pentyl ring adopts a conformation between envelope and half‐chair. The overall conformation is defined by the spatial arrangement of the ring moieties.