7 Antimicrobial Activity and Action of Silver

Russell, A. D.; Hugo, W. B.

doi:10.1016/s0079-6468(08)70024-9

Cited by 906 publications

(614 citation statements)

References 82 publications

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“…Ag + ions have a high affinity to phosphate groups present in nucleic acids, thus inhibiting the replication of bacterial DNA [31][32][33]. Uncomplexed silver strongly binds to cell proteins through thiol, amino, carboxyl, imidazole and phosphate groups [34]. Silver, however, after complexation with the carrier, can practically bind only to the -SH groups.…”

Section: Silver Complexes With Ty In the Supramolecular Cr Systemmentioning

confidence: 99%

Supramolecular Structures as Carrier Systems Enabling the Use of Metal Ions in Antibacterial Therapy

Natkaniec

Jagusiak

Rybarska

et al. 2017

Self-Assembled Molecules – New Kind of Protein Ligands

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The antimicrobial activity of metal ions, especially silver ions, has been known since ancient times. Consequently, finding an accessible, cheap and efficient carrier of metal ions remains an important challenge in molecular biology. The supramolecular system presented in this chapter consists of a mixture of Congo red and Titan yellow molecules forming a supramolecular ligand which is a potent complexing agent of silver ions. Delivery of ions in complex with supramolecular dye is advantageous due to the reduced toxicity. In addition, the use of Congo red provides selective action and -thanks to increased solubility -facilitates efficient dispersion of the carrier dye and excretion from the organism.

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Section: Silver Complexes With Ty In the Supramolecular Cr Systemmentioning

confidence: 99%

Supramolecular Structures as Carrier Systems Enabling the Use of Metal Ions in Antibacterial Therapy

Natkaniec

Jagusiak

Rybarska

et al. 2017

Self-Assembled Molecules – New Kind of Protein Ligands

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“…Interaction of ionic silver (which can be released from nAg) with thiol groups and formation of S-Ag or disulfide bonds can damage bacterial proteins, interrupt the electron transport chain, and dimerize DNA (Trevors, 1987;Russell and Hugo, 1994;Feng et al, 2000). Cells treated with non-lethal levels of silver ions show DNA aggregation in the cell (Feng et al, 2000), and cells that have been damaged by silver ions can be repaired with cysteine (Russell and Hugo, 1994). …”

Section: Antibacterial and Antiviral Properties Of Silver Nanoparticlmentioning

confidence: 99%

“…The antiviral properties of silver ions may involve interaction with viral DNA and thiol groups in proteins (Russell and Hugo, 1994). Silver ions have been shown to be effective antiviral agents towards MS2 (Yahya et al, 1992;Kim et al, 2008), a common indicator of enteroviruses used in water treatment models (Zhu et al, 2005).…”

Section: Antibacterial and Antiviral Properties Of Silver Nanoparticlmentioning

confidence: 99%

“…Silver toxicity to E. coli is altered by common water constituents that affect silver solubility and bioavailability, such as chloride, phosphates, sulfides, DOC, and compounds containing thiol groups. These compounds decrease the potency of silver ions and, in the case of cysteine, can reverse some of the damage to bacteria cells caused by silver (Russell and Hugo, 1994;Gupta and Silver, 1998;Butkus et al, 2005). Bactericidal action of silver ions also increases with increasing temperature and pH (Russell and Hugo, 1994), which are two important factors in water treatment process control.…”

Section: Enhanced Virus Removal By Nag-psf Membranesmentioning

confidence: 99%

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Polysulfone ultrafiltration membranes impregnated with silver nanoparticles show improved biofouling resistance and virus removal

et al. 2009

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“…Additionally, silver has been shown to interact with structural proteins and preferentially bind to DNA bases to inhibit replication (Richard et al, 2002;Russel and Hugo, 1994). The principal aim of this paper was to evaluate the performance and the characteristics of a commercially available activated carbon filter for water purification, bacteriostatic power of which was enriched with addition of metal silver.…”

Section: Introductionmentioning

confidence: 99%

Removal of radioisotopes in solution and bactericidal/bacteriostatic sterilising power in activated carbon and metal silver filters

Maioli

Bestetti

Mauri

et al. 2009

Environmental Toxicology and Pharmacology

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a b s t r a c tActivated carbon filters play an important role in water filtration and purification from contaminants of different origin. Their limit consists in bacterial proliferation, which may occur only during prolonged periods of non-use and in their ability to remove radioactive contaminants present in waste water from Industry or Nuclear Medicine departments.In this work we tested a commercially available activated carbon filter for water purification enriched with silver plated parts incubating in static condition at room temperature different micro organisms (Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa, Salmonella enteritidis, Staphylococcus aureus, Aspergillum niger), up to 78 days.The microbial growth was in general more inhibited in the presence of metal silver into the activated carbon in respect to filters with the activated carbon alone: >4 log inhibition of bacterial proliferation after 78 days of incubation the presence of silver vs. 2 log without silver. When the filters were incubated empty of carbon, the sterilizing power of silver was confirmed further.The activated carbon filters proved also their ability in removing from water the principal radioisotopes used for residues liquid medical and research purposes ( 131 I, 99m Tc, 201 Tl, 67 Ga).These results contribute useful data for the use of the silver-enriched carbon filters in water filtration both for daily use at home, and professional use in a Nuclear Medicine laboratory.

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7 Antimicrobial Activity and Action of Silver

Cited by 906 publications

References 82 publications

Supramolecular Structures as Carrier Systems Enabling the Use of Metal Ions in Antibacterial Therapy

Supramolecular Structures as Carrier Systems Enabling the Use of Metal Ions in Antibacterial Therapy

Polysulfone ultrafiltration membranes impregnated with silver nanoparticles show improved biofouling resistance and virus removal

Removal of radioisotopes in solution and bactericidal/bacteriostatic sterilising power in activated carbon and metal silver filters

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