7-[125I]Iodoclonazepam: Purification by high-performance liquid chromatography for use in a very sensitive benzodiazepine radioimmunoassay of broad specificity

Water analysis

“…An analytical database has been prepared for benzodiazepines and benzophenones (198) and a review which describes standardized chromatographic and immunological methods with special regard to the screening of some newer benzodiazepines has been published (199). Methods for the detection of benzodiazepines have included positive-and negative-ion MS (200), GC-ECD (201), dual capillary column and dual GC-NPD (202), HPLC/RIA (203), HPLC-ECD (204), EMIT (205), EMIT-st and TDx (206), EMIT-st and TLC (207), and a chemiluminescence immunoassay (208). A rapid method for the isolation of various benzodiazepines from human samples with Sep-Pak C18 cartridges before wide-bore capillary GC has been described (209).…”