“…Hypo-fractionated radiotherapy can be administered in 2–5 fractions if the size of the tumor is too large or the dose is above the limit radiation dose to surrounding normal organs [6], [7]. With sophisticated radiation treatment techniques such as SRS and hypo-fractionated radiotherapy, imaging guidance systems, such as ExacTrac (BrainLAB, Feldkirchen, Germany) and cone-beam computed tomography (CBCT; Varian Medical System, CA, USA; Elekta Oncology System, Crawley, UK) are indispensable, as they improve the accuracy of patient localization setup and tumor targeting in contouring [8], [9], [10], [11], [12], [13]. …”