Abstract:Aim: The present study aimed at the development of valsartan floating tablets (VFTs) using Ocimum basilicum mucilage (OBM) and hydroxypropyl methylcellulose (HPMC) K100M by applying response surface methodologybased 3 2 factorial design. Materials and Methods: OBM (A) and HPMC K100M (B) were selected as independent factors, and swelling index (Y 1 ) and time taken for 90% drug release (Y 2 ) were as responses. Experimentally designed 9 runs assessed for Y 1 and Y 2 , and analysis of variance (ANOVA) was applie… Show more
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