“…The implementation of PSMA ligand imaging has substantially improved the diagnostic accuracy for the detection of (oligo) metastatic PCa at low PSA levels [5,22], leading to the recent guidelines by the European Organization for Research and Treatment of Cancer (EORTC) demanding modern imaging methods for trials investigating MDT in oligometastatic PCa [23]. Although large randomized prospective studies are lacking, approximately two-thirds of the experts at the 2017 Advanced Prostate Cancer Consensus Conference considered MDT ADT androgen deprivation therapy, CF-RT conventionally fractionated radiotherapy type, Gy Gray, LNs lymph node metastases, PCa prostate cancer, PSMA-PET prostate-specific membrane antigen positron emission tomography, PSA prostate-specific antigen, RP radical prostatectomy, sRT salvage radiotherapy, SBRT stereotactic body radiation therapy, SIB simultaneous integrated boost as a treatment option for patients with oligorecurrent PCa [13].…”