662 Dupilumab associated facial and neck erythema

Dupilumab-associated facial erythema successfully treated with oral ivermectin

“…Face and neck dermatitis (FND) in atopic dermatitis is a diagnostic challenge in which dupilumab adds a new grade of complexity [2]. In a recent systematic review of 101 patients with DFE, 45% of patients reported different cutaneous symptoms from preexisting atopic dermatitis [3]. Diverse In a retrospective study of 94 patients with dupilumab [4], 6% presented rosacea-like folliculitis and increased demodex count in reflectance confocal microscopy [1,4].…”

“…Dupilumab-associated facial erythema (DFE) has been described in 10% of patients and can lead to dupilumab discontinuation [1]. Etiology remains unclear and treatment is challenging [1][2][3]. Here we present a patient with DFE successfully treated with oral ivermectin.…”