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Abstract

The relationships of critical nutrients such as plant phenolics, vitamins, minerals and lipids are considered with respect to the incidence of a variety of cancers, and analyzed in terms of how these nutrient deficiencies alter immune function, DNA integrity and cell proliferation. With a significant correlation found between cancer and these nutrient deficiencies, the hypothesis is presented here that nutrition could provide a unifying perception of cancer and recast it as a single disease. This further suggests that a coordinated administration of specific, critical nutrients to cancer patients could lead to the reversal of the disease. It is also proposed that the concurrent presence of a variety of nutritional deficiencies in cancer patients requires a multilevel, systemic approach to this disease as opposed to the single active therapeutic agent approach that is the cornerstone of contemporary research and pharmacology.

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“…Stress also down-regulates the digestive functions of the gut, including those of the stomach and pancreas. This in turn suppresses the uptake of critical nutrients that are essential for genomic stability [ 14 ]. It was reported that breast cancer patients as a group exhibit a depressed thyroid function [ 14 ], suggesting an etiological role for thyroid deficiency in neoplasia.…”

“…This in turn suppresses the uptake of critical nutrients that are essential for genomic stability [ 14 ]. It was reported that breast cancer patients as a group exhibit a depressed thyroid function [ 14 ], suggesting an etiological role for thyroid deficiency in neoplasia. Thyroid function is profoundly affected by the iodine supply, and thyroid, breast and gastric cancers have been linked to iodine deficiency [ 14 ].…”

“…It was reported that breast cancer patients as a group exhibit a depressed thyroid function [ 14 ], suggesting an etiological role for thyroid deficiency in neoplasia. Thyroid function is profoundly affected by the iodine supply, and thyroid, breast and gastric cancers have been linked to iodine deficiency [ 14 ]. Previously we have pointed out that critical nutrient deficiencies mimic the effects of chemical or radiation damage to DNA, and suggested that the correction of these deficiencies could reverse the progression of malignant proliferation [ 14 ].…”

“…These theories do not generally take into account the demonstrated importance of environmental factors in human cancer development. In a previous paper [ 14 ] we have shown that specific dietary deficiencies mimic the effects of chemical or radiation damage to DNA, which we propose plays an important role in human carcinogenesis and tumorigenesis. This observation allows us to consider cancer as a single disease, possibly developing from a single cancer stem cell.…”

Xylan/polyvinyl alcohol blend and its performance as hydrogel

“…Hemicelluloses have been reported to be used as a beater additive in papermaking4 and as a source of xylitol 5. They have also found potential use as food additives, thickeners, emulsifiers, and a cancer protective agents 6, 7. Xylose, a pentose sugar repeating unit of xylan, contains two easily accessible hydroxyl groups, offering various possibilities for chemical modifications, for example, benzylation,8 methacrylation,9 acetylation,2, 10 long‐chain acylation,11 and succinoylation 12, 13.…”