6. Oral Contraceptives

Petursson, Gissur; Fraunfelder, F. T.; Meyer, S. Martha

doi:10.1016/s0161-6420(81)35032-5

Cited by 23 publications

(4 citation statements)

References 11 publications

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“…Oftentimes there are preexisting vascular factors such as systemic hypertension and/or diabetes mellitus. Evidence regarding this association is conflicting but 1 large study showed that there is an increase in retinal vascular findings 307–309…”

Section: Vascular Relatedmentioning

confidence: 99%

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The Impact of Systemic Medications on Retinal Function

Somisetty

Santina

Sarraf

et al. 2023

Asia-Pacific Journal of Ophthalmology

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This study will provide a thorough review of systemic (and select intravitreal) medications, along with illicit drugs that are capable of causing various patterns of retinal toxicity. The diagnosis is established by taking a thorough medication and drug history, and then by pattern recognition of the clinical retinal changes and multimodal imaging features. Examples of all of these types of toxicity will be thoroughly reviewed, including agents that cause retinal pigment epithelial disruption (hydroxychloroquine, thioridazine, pentosan polysulfate sodium, dideoxyinosine), retinal vascular occlusion (quinine, oral contraceptives), cystoid macular edema/retinal edema (nicotinic acid, sulfa-containing medications, taxels, glitazones), crystalline deposition (tamoxifen, canthaxanthin, methoxyflurane), uveitis, miscellaneous, and subjective visual symptoms (digoxin, sildenafil). The impact of newer chemotherapeutics and immunotherapeutics (tyrosine kinase inhibitor, mitogen-activated protein kinase kinase, checkpoint, anaplastic lymphoma kinase, extracellular signal-regulated kinase inhibitors, and others), will also be thoroughly reviewed. The mechanism of action will be explored in detail when known. When applicable, preventive measures will be discussed, and treatment will be reviewed. Illicit drugs (cannabinoids, cocaine, heroin, methamphetamine, alkyl nitrite), will also be reviewed in terms of the potential impact on retinal function.

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Section: Vascular Relatedmentioning

confidence: 99%

“…Evidence regarding this association is conflicting but 1 large study showed that there is an increase in retinal vascular findings. [307][308][309] Vancomycin (Intracameral)…”

Section: Oral Contraceptivesmentioning

confidence: 99%

The Impact of Systemic Medications on Retinal Function

Somisetty

Santina

Sarraf

et al. 2023

Asia-Pacific Journal of Ophthalmology

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“…42 However, retinal vein occlusions associated with these medications are more common with older formulations that are no longer in use.…”

Section: Estrogen and Progesteronementioning

confidence: 99%

Retinal Toxicity of Systemic Medications

Labriola

Jeng²,

Fawzi

2012

International Ophthalmology Clinics

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“…Chizek and Franceschetti (1969) considered that the signs and symptoms which were reportedly due to the contraceptive pill could be due to overwear, humidity changes and infection. Peturrson, Fraunfelder and Meyer (1981) reviewed the evidence for the relationship between contact lens intolerance and oral contraceptives. A prospective study of 517 patients failed to show any difference in contact lens tolerance between patients taking the pill and those who were not.…”

Section: Ocular Adverse Effectsmentioning

confidence: 99%

Adverse ocular reactions to drug therapy

Davies¹

1989

The Actions and Uses of Ophthalmic Drugs

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6. Oral Contraceptives

Cited by 23 publications

References 11 publications

The Impact of Systemic Medications on Retinal Function

The Impact of Systemic Medications on Retinal Function

Retinal Toxicity of Systemic Medications

Adverse ocular reactions to drug therapy

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