6-Chloro-2-hydroxy-2-trifluoromethyl-2H-chromene-3-carboxylic acid (5-allylsulfanyl-[1,3,4]thiadiazol-2-yl)-amide

Wang, Caixia; Chen, Xu; Yang, Gangyi; Fan, Sufang; Li, Xin; Guo, Tingting

doi:10.3390/m830

Cited by 2 publications

(3 citation statements)

References 19 publications

(16 reference statements)

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“…In this study ,all (10) V. cholerae isolates were investigated biotyping and the results showed that all V. choleraee were O1(Eltor) serotype group (16).Our results was in agreement with the results obtained by (22) .…”

Section: Table (1): Biochemical Tests Of V Choleraee Isolatessupporting

confidence: 90%

“…Three isolates V. cholerae (3,5,6)were selected depending on results of antibiotics sensitivity tests as showed multiple -antibiotics resistance(100%). Results agreed with (22) who found that the V. choleraee isolates showed a high sensitivity to each of Ampicillin, Ciprofloxacin, Erythromycine , Tetracycline, Gentamicin and Cephalothin, and showed a low resistance (10%) and (20%) to Cefotaxime and Amikacin respectively, but disagreed with her results when she found that (80%) of the environmental isolates were resistance to Amikacin.…”

Section: Antibiotics Susceptibilitysupporting

confidence: 76%

“…because of various biological activities such as antiviral, anti-tumor, anti-bacterial, fungicidal, antiflamatory, antioxidative and activator of potassium channels effects (22) .Coumarin (2H-1-benzopyran-2-one), a naturally occurring plant constituent, has been used in the treatment of cancer and edema, and many of its derivatives have also shown biological activity. include antibacterial (23) .…”

Section: Tcbs Mediummentioning

confidence: 99%

See 2 more Smart Citations

The Effect of Coumarin Derivatives(compounds) on the Vibrio cholerae Isolates from Different Clinical Iraqi Sources

Abdul¹,

Taher²,

Hassan³

et al. 2017

IJPS

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From a large number of bacterial samples collected from different hospital in Iraq in central health laboratory ,only ten isolates were identified primary as Vibrio. A number of morphology and biochemical test were carried out to complete this identification that showed all bacterial isolates were related to Vibrio cholerae .In this study all Vibrio isolates were investigated for Bio typing and the result showed that all (10) isolate were related to (Eltor biotypes) .Also, the susceptibility test towards eight antibiotics were carried out . Results shows that ciprofloxacin , Norfloxacin, Erythromycin, Ampicillin, ceftriaxone and Amikacin were the most effective antibiotics and their resistance percentage were 20%,20%,20, 20,30% and 30% respectively ,While Chloramphenicol and Co- trimoxazole were less effective and their resistance percentage were 90% both of them. Three (3,5,6) isolates V. cholerae were selected depending on results of antibiotics sensitivity tests as showed multiple â€“antibiotics resistance(100%). Then tested to study the effect of coumarin derivatives compounds (1, 2, 3 ) which showed inhibitory effect on V. cholera (3,5,6) isolates and the compound ( 3 ) showed the highest antibacterial activity of (12,15,14 mm) of inhibition zone diameter against V. cholera (3,5,6) isolates respectively. Also, these Iraqi isolates (3,5,6) used to test the effect of acridine orange (0.1%) as acuring agent , the results showed that all (3) isolates V. cholerae were sensitive to (ciprofloxacin, ceftrixone and Norfloxacin), While the rest were resistance to remained five antibiotics. The results of Agarose â€“gel electrophoresis of both normal V. cholerae (3,5,6) and cured isolates showed the presence of chromosomal and plasmid DNA bands in the normal case ,While only chromosomal DNA bands occur with V. cholerae (isolate 8) treated with an acridine orange at concentration of (10-2 to 10-4).

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Section: Table (1): Biochemical Tests Of V Choleraee Isolatessupporting

confidence: 90%