Antimycotic activity of acidic, basic and neutral fractions of petrol, ether and chloroform extracts of 27 plant species (30 plant parts) with a total of 270 fractions is reported. Activity was recorded in 12.5%, mostly (57%) in the chloroform fractions, followed by ether (31.5%), while petrol fractions were the least active (11.5%). On the whole, 56% of the acids/phenols, 14% basic and 30% of the neutral fractions exhibited activity. None of the aqueous residual fractions showed any significant activity. An attempt was made to correlate the activity of the fraction with the class of compounds it contained.
Antimycotic TestsTrichophyton mentagrophytes and Candida albicans were obtained from the stock culture of the Department Pharmaceutical Biology Downloaded from informahealthcare.com by CDL-UC San Diego on 08/23/15For personal use only.